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Strain Registration

Strain: SPRD.WKY-(D5Rat190-D5Rat114)/Ibmm

Symbol: SPRD.WKY-(D5Rat190-D5Rat114)/Ibmm
Strain: SPRD.WKY-(D5Rat190-D5Rat114)
Substrain: Ibmm
RGD ID: 1599763
Citation ID: RRID:RGD_1599763
Ontology ID: RS:0001452
Previously known as: SPRD.WKY-(D5Rat190-D5Rat114)/Ibmm; SPRD-Cu3.WKY-D5Rat190/D5Rat114; SPRD-Cu3.WKY-Mcstm1; C5.Mcstm1
Type: congenic
Source: Universite Libre de Bruxelles, Institut de Biologie et de Medecine Moleculaires, Gosselies, Belgium
Origin: SPRD/HanZtm were crossed with WKY/Han and F1 males were backcrossed with SPRD/HanZtm. Heterozygous carriers were bred to SPRD/HanZtm.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0529,109,097 - 29,109,277RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4524,978,084 - 24,978,263RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Mammary cancer resistance and precocious mammary differentiation in the WKY rat: identification of 2 quantitative trait loci. Lella V, etal., Int J Cancer. 2007 Oct 15;121(8):1738-43.
2. Contrasting epistatic interactions between rat quantitative trait loci controlling mammary cancer development. Piessevaux G, etal., Mamm Genome. 2008 Dec 4.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines
4. Isolation of two regions on rat chromosomes 5 and 18 affecting mammary cancer susceptibility. Stieber D, etal., Int J Cancer. 2007 Jan 17;.

Region

Position Markers

Flank 1 / 1 (D5Rat190)
Rat AssemblyChrPosition (strand)Source
Rnor_5.0529,109,097 - 29,109,277NCBI
RGSC_v3.4524,978,084 - 24,978,263RGD
RGSC_v3.1524,978,084 - 24,978,263RGD
SHRSP x BN Map515.95RGD
SHRSP x BN Map515.95UniSTS

Flank 2 / 1 (D5Rat114)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map5965.4RGD
RH 3.4 Map5965.4UniSTS
SHRSP x BN Map580.7699UniSTS
SHRSP x BN Map580.7699RGD
Strain QTL Data
Symbol Name Trait
Mamtr5 Mammary tumor resistance QTL 5 mammary gland integrity trait   (VT:0010552)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease partially resisitant to chemically induced mammary cancinogenesis 1643011