Strain Report - Rat Genome Database

Name: WKY.GHS-( D1Rat32-D1Mit32 )
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: WKY.GHS-(D1Rat32-D1Mit32)

Symbol:

WKY.GHS-(D1Rat32-D1Mit32)

Strain:

WKY.GHS-(D1Rat32-D1Mit32)

RGD ID:

1598804

Citation ID:

RRID:RGD_1598804

Ontology ID:

RS:0001597

Previously known as:

WKY.GHS-(D1Rat32-D1Mit32); WKY.GHS(RNO1)

Type:

congenic

Source:

Department of Medicine and Physiology, University of Rochester, Rochester New York

Origin:

GHS females were crossed with WKY males and the heterozygous males were backcrossed to WKY females for 10 generations this resulted in introgressing a 100 cM region of chr 1 which contained the Hc1 QTL

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	244,113,147 - 244,113,296	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	1	195,598,053 - 265,002,735	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	1	202,649,657 - 272,443,364	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	1	112,148,733 - 250,430,505	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased urine calcium level (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

Options:

View chart

Download data table

View expanded data table

Clinical Measurement

urine calcium excretion rate

References

References - curated

#	Reference Title	Reference Citation
1.	Isolation and confirmation of a calcium excretion quantitative trait locus on chromosome 1 in genetic hypercalciuric stone-forming congenic rats.	Hoopes RR Jr, etal., J Am Soc Nephrol. 2006 May;17(5):1292-304. Epub 2006 Apr 12.
2.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D1Rat32)

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	195,598,053 - 195,598,217	NCBI
Rnor_5.0	1	202,649,657 - 202,649,821	UniSTS
RGSC_v3.4	1	112,148,733 - 112,149,024	RGD
RGSC_v3.4	1	112,148,806 - 112,148,970	UniSTS
RGSC_v3.1	1	112,227,076 - 112,227,367	RGD
Celera	1	105,238,688 - 105,238,852	UniSTS
RH 3.4 Map	1	907.99	UniSTS
RH 3.4 Map	1	907.99	RGD
SHRSP x BN Map	1	53.8299	RGD
SHRSP x BN Map	1	53.8299	UniSTS
FHH x ACI Map	1	55.58	RGD
Cytogenetic Map	1		RGD

Flank 2 / 1 (D1Mit32)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	244,113,147 - 244,113,296 (+)	MAPPER
Rnor_6.0	1	265,002,587 - 265,002,735	NCBI
Rnor_5.0	1	272,443,216 - 272,443,364	UniSTS
RGSC_v3.4	1	250,430,357 - 250,430,505	UniSTS
RGSC_v3.4	1	250,430,356 - 250,430,505	RGD
RGSC_v3.1	1	250,690,926 - 250,691,074	RGD
Celera	1	239,924,098 - 239,924,246	UniSTS
RH 3.4 Map	1	1623.2	RGD
RH 3.4 Map	1	1623.2	UniSTS
RH 2.0 Map	1	1220.0	RGD
SHRSP x BN Map	1	139.09	RGD

Strain QTL Data

Symbol	Name	Trait
Hc6	Hypercalciuria QTL 6	urine calcium amount (VT:0002985)

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_characteristics	Higher levels of urine calcium excretion is seen as compared to the parental WKY.	1582396

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: WKY.GHS-(D1Rat32-D1Mit32)

Mammalian Phenotype

Related Phenotype Data for Term "WKY.GHS-(D1Rat32-D1Mit32)" (RS:0001597)