Strain Report - Rat Genome Database

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Strain: ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur

Symbol: ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur
Strain: ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)
Substrain: Eur
RGD ID: 1598799
Citation ID: RRID:RGD_1598799
Ontology ID: RS:0001166
Also Known As: Rf-1B+5; ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur; ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur
Type: congenic
Available Source: Not Available
Origination: Department of Pediatric Surgery, Erasmus Medical Center, Rotterdam, Netherlands
Description: Triple congenic strain which was generated using the speed congenic strategy by backcrossing ACI/Eur and FHH/Eur parental strains. Rf1 QTL region of chr 1 and Rf5 QTL region of chr 17 are introgressed in this strain.
Last Known Status: Unknown

Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. Absence of an interaction between the Rf-1 and Rf-5 QTLs influencing susceptibility to renal damage in rats. van Dijk SJ, etal., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12.


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other Renal damage susceptibility is similar to other congenic strains which have the Rf-1 region. 1582571
strain_phys_biochem These have impaired renal autoregulation. 1582571