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Strain Registration

Strain: BBDP/WorN

Symbol: BBDP/WorN
Strain: BBDP
Substrain: WorN
RGD ID: 1598798
Citation ID: RRID:RRRC_00092
Ontology ID: RS:0001183
Type: inbred
Source: NIH Autoimmune Rat Model Repository and Dev Ctr
Origin: Diabetes prone BB rats maintained in NIH. Developed from a closed colony of outbred wistar rats which spontaneously developed autoimmune diabetes mellitus at the Bio-Breeding Laboratories, Ontario. University of Massachusetts Medical Center started inbreeding these in 1977. In 1983 NIH established a reference colony from this inbred colony.
Last Known Status: Extinct (as of 2021-02-22)





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Diabetes-Prone and Diabetes-Resistant BB Rats: Animal Models of Spontaneous and Virally Induced Diabetes Mellitus, Lymphocytic Thyroiditis, and Collagen-Induced Arthritis Guberski D L, ILAR Journal V35(2) 1993
2. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Damaging Variants
Number of Damaging Variants
SamplemRatBN7.2Rnor_6.0Rnor_5.0RGSC_v3.4
BBDP/WorN (ICL) 442
BBDP/WorN (KNAW) 473
BBDP/Wor (RGD) 686


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Diabetes develops between 60-120 days of age in both the sexes with an 86% overall incidence 1578691
strain_other Reported to be extinct from the Rat Resource & Research Center as of 26/08/2011. 2292495
strain_reproduction Onset of diabetes occurs during pregnancy so these have reduced productivity. 1578691

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-03 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2015-04-03 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2014-11-06 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2014-11-06 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2013-04-16 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2013-04-16 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2012-04-05 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2012-04-05 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2011-08-26 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED
2011-08-26 BBDP/WorN    BBDP/WorN    Name updated 68913 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00092 RGD