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Strain: WKY/Bbb

Symbol: WKY/Bbb
Strain: WKY
Substrain: Bbb
RGD ID: 1581635
Citation ID: RRID:RGD_1581635
Ontology ID: RS:0001601
Also Known As: WKY-0HD; MDC-01-82; WKY-0
Type: inbred
Available Source: Not Available
Origination: Max - Delbruck - Center for Molecular Medicine, Germany
Description: This WKY colony was obtained from the Japanese colony in 1974. Now this is maintained at University of Heidelberg, Heidelburg, Germany.
Last Known Status: Unknown





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Mammalian Phenotype

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References

References - curated
# Reference Title Reference Citation
1. Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1. Hubner N, etal., Hypertension 1999 Oct;34(4 Pt 1):643-8.
2. Genome-wide searches for blood pressure quantitative trait loci in the stroke-prone spontaneously hypertensive rat of a Japanese colony. Kato N, etal., J Hypertens 2003 Feb;21(2):295-303.
3. Evidence for primary genetic determination of heart rate regulation: chromosomal mapping of a genetic locus in the rat. Kreutz R, etal., Circulation 1997 Aug 19;96(4):1078-81.
4. Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10. Kreutz R, etal., Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8778-82.
5. Interaction between blood pressure quantitative trait loci in rats in which trait variation at chromosome 1 is conditional upon a specific allele at chromosome 10. Monti J, etal., Hum Mol Genet 2003 Feb 15;12(4):435-9.
6. RGD Strain RSO annotation pipeline RGD Automated Pipelines
7. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other Used as a normotensive reference strain in cardiovascular research. 619633