Strain Report - Rat Genome Database

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Strain: SS.LEW-(D10Chm10-D10Rat11)/Ayd

Symbol: SS.LEW-(D10Chm10-D10Rat11)/Ayd
Strain: SS.LEW-(D10Chm10-D10Rat11)
Substrain: Ayd
RGD ID: 1579903
Citation ID: RRID:RGD_1579903
Ontology ID: RS:0001507
Previously known as: C10S.L16;SS.LEW-(D10Rat13-D10Rat11)/Ayd; SS.LEW-(D10Rat13-D10Rat11)/Ayd; SS.LEW-(D10Chm10-D10Rat11)/Ayd; c10s.l16
Type: congenic
Source: Research Centre, Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal, Quebec, Canada
Origin: A congenic substrain derived from the progenitor strain SS.LEW-(D10Rat119-D10Mgh1)/Ayd.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21092,698,959 - 96,121,100RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01095,967,019 - 99,492,409RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01095,701,164 - 99,184,250RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41097,152,234 - 100,633,982RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension. Charron S, etal., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.
2. Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci. Chauvet C, etal., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.
3. Submegabase resolution of epistatically interacting quantitative trait loci for blood pressure applicable for essential hypertension. Chauvet C, etal., J Hypertens. 2008 May;26(5):893-901.
4. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.
5. Neuronal Responsiveness to Central Na+ in 2 Congenic Strains of Dahl Salt-Sensitive Rats. Huang BS, etal., Hypertension. 2007 Apr 9;.
6. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Position Markers

Flank 1 / 1 (D10Rat13)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21092,698,959 - 92,699,242 (+)MAPPER
Rnor_6.01095,967,019 - 95,967,298NCBI
Rnor_5.01095,701,164 - 95,701,443UniSTS
RGSC_v3.41097,152,256 - 97,152,538UniSTS
RGSC_v3.41097,152,234 - 97,152,587RGD
RGSC_v3.11097,166,626 - 97,166,908RGD
Celera1091,364,444 - 91,364,676UniSTS
RH 3.4 Map101030.5RGD
RH 3.4 Map101030.5UniSTS
RH 2.0 Map101136.8RGD
SHRSP x BN Map1073.35RGD
FHH x ACI Map1076.87RGD
Cytogenetic Map10q32.1UniSTS

Flank 2 / 1 (D10Rat11)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21096,120,911 - 96,121,100 (+)MAPPER
Rnor_6.01099,492,217 - 99,492,409NCBI
Rnor_5.01099,184,058 - 99,184,250UniSTS
RGSC_v3.410100,633,512 - 100,633,982RGD
RGSC_v3.410100,633,654 - 100,633,848UniSTS
RGSC_v3.110100,648,024 - 100,648,218RGD
Celera1094,766,403 - 94,766,596UniSTS
RH 3.4 Map101084.8UniSTS
RH 3.4 Map101084.8RGD
RH 2.0 Map101218.2RGD
SHRSP x BN Map1077.15RGD
FHH x ACI Map1082.4RGD
Strain QTL Data
Symbol Name Trait
Am13 Aortic mass QTL 13 aorta mass   (VT:0002845)    
Bp310 Blood pressure QTL 310 arterial blood pressure trait   (VT:2000000)    
Cm107 Cardiac mass QTL 107 heart mass   (VT:0007028)    
Cm108 Cardiac mass QTL 108 heart left ventricle mass   (VT:0007031)    
Cm109 Cardiac mass QTL 109 heart right ventricle mass   (VT:0007033)    
Kidm67 Kidney mass QTL 67 kidney mass   (VT:0002707)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_phys_biochem Strain showed mean arterial pressure of 150 mmHg which was decreased from parental SS strain but higher than progenitor congenic strain SS.LEW-(D10Rat119-D10Mgh1)/Ayd 1559293

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-08 SS.LEW-(D10Chm10-D10Rat11)/Ayd    SS.LEW-(D10Chm10-D10Rat11)/Ayd    Name updated 68913 APPROVED
2013-11-20 SS.LEW-(D10Chm10-D10Rat11)/Ayd    SS.LEW-(D10Rat13-D10Rat11)/Ayd    Name updated 68913 APPROVED
2013-11-20 SS.LEW-(D10Chm10-D10Rat11)/Ayd    SS.LEW-(D10Rat13-D10Rat11)/Ayd    Name updated 68913 APPROVED
2013-11-20 SS.LEW-(D10Chm10-D10Rat11)/Ayd    SS.LEW-(D10Rat13-D10Rat11)/Ayd    Symbol updated 68687 APPROVED
2013-11-20 SS.LEW-(D10Chm10-D10Rat11)/Ayd    SS.LEW-(D10Rat13-D10Rat11)/Ayd    Symbol updated 68687 APPROVED