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Strain Registration

Strain: SS.LEW-(D10Chm224-D10Chm6)/Ayd

Symbol: SS.LEW-(D10Chm224-D10Chm6)/Ayd
Strain: SS.LEW-(D10Chm224-D10Chm6)
Substrain: Ayd
RGD ID: 1579901
Citation ID: RRID:RGD_1579901
Ontology ID: RS:0001513
Previously known as: C10S.L20; SS.LEW-(D10Chm224-D10Chm6)/Ayd; SS.LEW-(D10Chm224-D10Chm6)/Ayd; c10s.l20
Type: congenic
Source: Research Centre, Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal, Quebec, Canada
Origin: A sub congenic strain derived from the progenitor strain SS.LEW-(D10Wox51-D10Rat27)/Ayd.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,508,825 - 72,509,024RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01075,001,953 - 76,556,637RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01075,100,237 - 76,438,561RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41074,705,355 - 76,000,447RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension. Charron S, etal., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.
2. Submegabase resolution of epistatically interacting quantitative trait loci for blood pressure applicable for essential hypertension. Chauvet C, etal., J Hypertens. 2008 May;26(5):893-901.
3. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D10Chm224)
Rat AssemblyChrPosition (strand)Source
Rnor_5.01076,309,595 - 76,309,841UniSTS
RGSC_v3.41074,705,355 - 74,705,601UniSTS
Celera1070,214,239 - 70,214,485UniSTS
Cytogenetic Map10q26UniSTS

Flank 2 / 1 (D10Chm6)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21072,508,825 - 72,509,024 (+)MAPPER
Rnor_6.01076,556,439 - 76,556,637NCBI
Rnor_6.01075,001,953 - 75,002,151NCBI
Rnor_5.01075,100,237 - 75,100,435UniSTS
Rnor_5.01076,438,363 - 76,438,561UniSTS
RGSC_v3.41076,000,249 - 76,000,447UniSTS
Celera1071,422,487 - 71,422,685UniSTS
Cytogenetic Map10q26UniSTS
Strain QTL Data
Symbol Name Trait
Am14 Aortic mass QTL 14 aorta mass   (VT:0002845)    
Bp279 Blood pressure QTL 279 arterial blood pressure trait   (VT:2000000)    
Bw185 Body weight QTL 185 body mass   (VT:0001259)    
Cm110 Cardiac mass QTL 110 heart mass   (VT:0007028)    
Cm111 Cardiac mass QTL 111 heart left ventricle mass   (VT:0007031)    
Cm112 Cardiac mass QTL 112 heart right ventricle mass   (VT:0007033)    
Kidm68 Kidney mass QTL 68 kidney mass   (VT:0002707)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_phys_biochem Strain showed mean arterial pressure of 144 mmHg which was decreased from parental SS strain but increased from progenitor congenic strain SS.LEW-(D10Wox51-D10Rat27)/Ayd. 1559293