Strain Report - Rat Genome Database

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Strain: BG

Symbol: BG
Strain: BG
Full Name: anemic Belgrade
RGD ID: 1578699
Citation ID: RRID:RRRC_00072
Ontology ID: RS:0001606
Also Known As: B
Type: inbred
Available Source: Rat Resource and Research Center
Description: These are descendants of the original Belgrade colony which was obtained by K. Kellar Centers forDisease Control and Prevention, Atlanta, GA. These were backcrossed with Harlan Sprague-Dawley Wistar and then amintained as a closed colony in Buffalo, NY.
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Fleming MD, etal., Proc Natl Acad Sci U S A 1998 Feb 3;95(3):1148-53.
2. Iron supplementation moderates but does not cure the Belgrade anemia. Garrick M, etal., Biometals. 1997 Apr;10(2):65-76.
3. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines
5. A thalassemia-like disorder in Belgrade laboratory rats. Sladic-Simic D, etal., Ann N Y Acad Sci. 1969 Nov 20;165(1):93-9.

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease They have autosomal recessively inherited microcytic hypochromic anemia which is associated with abnormal reticulocyte iron uptake. 729808
Database Acc Id Source(s)
RRRC RRRC:00072 RGD