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Strain: SS-Chr 3BN.Il2rgem1Mcwi/Mcwi

Symbol: SS-Chr 3BN.Il2rgem1Mcwi/Mcwi
Strain: SS-Chr 3BN.Il2rgem1Mcwi
Substrain: Mcwi
RGD ID: 155791425
Citation ID: RRID:RGD_155791425
Ontology ID: RS:0005353
Alleles: Il2rgem1Mcwi
Also Known As: SS-Chr 3BN.Il2rgem1Mcwi/Mcwi; SS-Chr 3^[BN].Il2rg^[em1Mcwi]/Mcwi
Type: mutant
Available Source: Not Available
Origination: Medical College of Wisconsin
Description: The IL2Rg gene was targeted in the SS/JrHsdMcwi rat by TALEN injection into single-cell rat embryos. Once established, a homozygous (RGD:12790632) female rat from the SSIL2Rg line was intercrossed with a homozygous SS.BN3 (RGD:1358154) male to yield heterozygous SS.BN3IL2Rg offspring (F1), followed by brother-sister mating to yield homozygous SS. BN3IL2Rg offspring by the F3 generation. This strain is Immunodeficient Ilrg (X-SCID) mutant consomic line.
Genetic Status: Homozygous
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X66,398,567 - 66,398,585RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X71,165,378 - 71,169,078RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X72,017,856 - 72,021,516RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4X89,342,055 - 89,345,715RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Dynamic NIR Fluorescence Imaging and Machine Learning Framework for Stratifying High vs. Low Notch-Dll4 Expressing Host Microenvironment in Triple-Negative Breast Cancer. Shafiee S, etal., Cancers (Basel). 2023 Feb 25;15(5):1460. doi: 10.3390/cancers15051460.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-30 SS-Chr 3BN.Il2rgem1Mcwi/Mcwi    SS-Chr 3BN-Il2rgem1Mcwi/Mcwi    Symbol and/or name change 68913 APPROVED
2023-05-16 SS-Chr 3BN-Il2rgem1Mcwi/Mcwi    SS-Chr 3BN-Il2rgem1Mcwi/Mcwi    Symbol and/or name change 68913 APPROVED
2022-12-15 SS-Chr 3BN-Il2rgem1Mcwi/Mcwi    SS-Chr 3BN-Il2rg/Mcwi    Symbol and/or name change 68913 APPROVED