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Strain Registration

Strain: CD-Ctnsem3Vjupk

Symbol: CD-Ctnsem3Vjupk
Strain: CD-Ctnsem3
Substrain: Vjupk
RGD ID: 155630633
Citation ID: RRID:RGD_155630633
Ontology ID: RS:0005172
Alleles: Ctnsem3Vjupk
Also Known As: SD-Ctnsem3Vjupk; CtnsE3N-3Vjupk/Vju rat; CD-Ctns^[em3Vjupk]
Type: mutant
Available Source: Not Available
Origination: Vernon Jansen Unit, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
Description: The mutant rat was produced by injecting Crl:CD(SD) zygotes with gRNA +Cas9 ribonucleoprotein complex targeting exon 3 of rat Ctns. The founder of this strain possessed a 8-bp insertion which results in frameshift and pre-mature stop truncated protein.
Genetic Status: Heterozygous
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21057,801,551 - 57,817,213RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01059,749,250 - 59,772,475RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01059,488,895 - 59,503,993RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41060,060,254 - 60,075,352RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Cystinosin-deficient rats recapitulate the phenotype of nephropathic cystinosis. Hollywood JA, etal., Am J Physiol Renal Physiol. 2022 Aug 1;323(2):F156-F170. doi: 10.1152/ajprenal.00277.2021. Epub 2022 Jun 13.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-12-05 CD-Ctnsem3Vjupk    SD-Ctnsem3Vjupk    Symbol and/or name change 68913 APPROVED