Strain Report - Rat Genome Database

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Strain: SD-Ccdc39em1Jgn

Symbol: SD-Ccdc39em1Jgn
Strain: SD-Ccdc39em1
Substrain: Jgn
RGD ID: 150520220
Citation ID: RRID:RGD_150520220
Ontology ID: RS:0005083
Alleles: Ccdc39em1Jgn
Previously known as: Ccdc39prh/prh
Type: mutant
Source: Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Origin: The CRISPR/Case9 system was desgined to create the progressive hydrocephalus (prh) mutation in Sprague Dawley rats. The homozygous rat carries chr2:g.120305679A>T change that creates a splice site (Ccdc39c.916+2T ) mutation in the rat Ccdc39 gene.
Genetic Status: Homozygous
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22116,665,261 - 116,703,364RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.02120,278,605 - 120,367,829RGD_MAPPER_PIPELINERnor6.0
Rnor_5.02139,933,049 - 139,971,476RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.42120,117,112 - 120,154,958RGD_MAPPER_PIPELINERGSC3.4

Disease Annotations     Click to see Annotation Detail View


References - curated
# Reference Title Reference Citation
1. Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam. Emmert AS, etal., Dis Model Mech. 2019 Nov 21;12(11). pii: 12/11/dmm040972. doi: 10.1242/dmm.040972.


Additional Information