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Strain: SHR-Gja8m1+/-Cub

Symbol: SHR-Gja8m1+/-Cub
Strain: SHR-Gja8m1+/-
Substrain: Cub
RGD ID: 150520205
Citation ID: RRID:RGD_150520205
Ontology ID: RS:0005077
Alleles: Gja8m1Cub
Previously known as: SHR-Dca+/-
Type: coisogenic
Source: Department of Biology, Charles University in Prague, Prague, Czech Republic
Origin: This strain is derived from SHR/OlaIpcv where a spontaneous mutation was observed in the NH2-terminal cytosolic domain of Cx50, L7Q. The connexin50 mutation in heterozygous state affects significantly the lipid profile and the oxidative stress parameters in SHR rats.
Genetic Status: Heterozygous
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Heterozygous connexin 50 mutation affects metabolic syndrome attributes in spontaneously hypertensive rat. Ĺ eda O, etal., Lipids Health Dis. 2016 Nov 21;15(1):199. doi: 10.1186/s12944-016-0376-3.


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