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Strain: WBN-Ht/Kob

Symbol: WBN-Ht/Kob
Strain: WBN-Ht
Substrain: Kob
RGD ID: 150520049
Citation ID: RRID:RGD_150520049
Ontology ID: RS:0005074
Type: congenic
Source: Not Available
Origin: The hairless rat was orginially found in JCL:Wistar rats at Ishikawa Laboratory Animal company, Saitama, Japan. Thereafter, hairless rats were backcrossed with WBN rats for 8 generations and the congenic strain of hairless rats has been established with a background of WBN at the company.
Last Known Status: Unknown

Disease Annotations     Click to see Annotation Detail View
alopecia  (IAGP)
dermatitis  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype


References - curated
# Reference Title Reference Citation
1. Locus of dominant hairless gene (Ht) causing abnormal hair and keratinization maps to rat chromosome 10. Akimoto T, etal., Exp Anim. 2000 Apr;49(2):137-40. doi: 10.1538/expanim.49.137.
2. WBN/Kob-Ht rats spontaneously develop dermatitis under conventional conditions: another possible model for atopic dermatitis. Asakawa M, etal., Exp Anim. 2005 Oct;54(5):461-5. doi: 10.1538/expanim.54.461.
3. Association of a mutation in TRPV3 with defective hair growth in rodents. Asakawa M, etal., J Invest Dermatol. 2006 Dec;126(12):2664-72. doi: 10.1038/sj.jid.5700468. Epub 2006 Jul 20.


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