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Strain: F344 -Aspaem34Kyo Hcn1em1Kyo

Symbol: F344 -Aspaem34Kyo Hcn1em1Kyo
Strain: F344 -Aspaem34 Hcn1em1
Substrain: Kyo
RGD ID: 150429634
Citation ID: RRID:RGD_150429634
Ontology ID: N/A
Alleles: Hcn1em1Kyo;   Aspaem34Kyo
Previously known as: F344 Aspaem34Kyo Hcn1em1Kyo
Type: mutant
Source: Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan
Origin: F344-Aspaem34Kyo (RGD:11564349) and F344-Hcn1em1Kyo (RGD:38676253) rats from the National BioResource Project-Rat were intercrossed to produce F1 hybrids and then to obtain F2 progeny. Rats homozygous for both Aspa and Hcn1 knockout alleles were selected from among F2 progeny and were used to generate the F344-Aspaem34Kyo/Hcn1em1Kyo double- knockout strain.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2249,495,771 - 49,899,702RGD_MAPPER_PIPELINEmRatBN7.2
mRatBN7.21057,891,704 - 57,945,267RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01059,839,693 - 59,888,244RGD_MAPPER_PIPELINERnor6.0
Rnor_6.0250,099,576 - 50,499,799RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01059,578,788 - 59,627,450RGD_MAPPER_PIPELINERnor5.0
Rnor_5.0268,473,431 - 68,874,494RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41060,178,509 - 60,199,207RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.4249,525,949 - 49,939,066RGD_MAPPER_PIPELINERGSC3.4

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Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
tremors  (IAGP)

References - curated
# Reference Title Reference Citation
1. Involvement of NMDA receptors in tremor expression in Aspa/Hcn1 double-knockout rats. Nishitani A, etal., Exp Anim. 2020 Nov 12;69(4):388-394. doi: 10.1538/expanim.20-0025. Epub 2020 Jun 5.


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-09-10 F344 -Aspaem34Kyo Hcn1em1Kyo    F344 Aspaem34Kyo Hcn1em1Kyo    Symbol and/or name change 68913 APPROVED