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Strain: F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi-/-

Symbol: F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi-/-
Strain: F344-Trpc4Tn(sb-T2/Bart3)2.192-/-
Substrain: Mcwi
RGD ID: 14696720
Citation ID: RRID:RRRC_00344
Ontology ID: RS:0004749
Also Known As: F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi-/+; TRPC4-/-; F344-Trpc4^[Tn(sb-T2/Bart3)2.192Mcwi-/-]
Type: mutant
Available Source: Rat Resource and Research Center
Origination: PhysGen, Transposagen
Description: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 1st intron of the Trpc4 gene. The heterozygotes were intercrossed to produce the homozygous mutant.
Last Known Status: Unknown





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References

References - curated
# Reference Title Reference Citation
1. A rat knockout model implicates TRPC4 in visceral pain sensation. Westlund KN, etal., Neuroscience. 2014 Mar 14;262:165-75. doi: 10.1016/j.neuroscience.2013.12.043. Epub 2014 Jan 3.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-19 F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi-/-    F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi-/+    Symbol and/or name change 68913 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00344 RGD