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Strain Registration

Strain: SD-Htr7em1Msu

Symbol: SD-Htr7em1Msu
Strain: SD-Htr7em1
Substrain: Msu
RGD ID: 14696715
Citation ID: RRID:RGD_14696715
Ontology ID: RS:0004746
Alleles: Htr7em1Msu
Also Known As: 5-HT7 KO; SD-Htr7^[em1Msu]
Type: mutant
Available Source: Not Available
Origination: Transgenic and Genome Editing Facility, and Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan
Description: CRISPR/Cas9 system was used to generate this mutant; this induced an 11 bp deletion in exon 1 and a 4 bp deletion in exon 2 of the Htr7 gene.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21233,636,442 - 233,761,063RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01254,547,964 - 254,671,811RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01261,759,122 - 261,879,914RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41240,136,279 - 240,260,620RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. Creation of the 5-hydroxytryptamine receptor 7 knockout rat as a tool for cardiovascular research. Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.
2. 5-HT does not lower blood pressure in the 5-HT7 knockout rat. Seitz BM, etal., Physiol Genomics. 2019 Jul 1;51(7):302-310. doi: 10.1152/physiolgenomics.00031.2019. Epub 2019 May 24.

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