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Strain: SD-Fhem1+/-

Symbol: SD-Fhem1+/-
Strain: SD-Fhem1+/SD-Fhem1-
RGD ID: 13792794
Citation ID: RRID:RGD_13792794
Ontology ID: RS:0004632
Alleles: Fhem1
Type: mutant
Source: Not Available
Origin: A pair of TALENs targeting exon 1 of the Fh gene was injected into SD embryos to create Fh knock out mutants. The resulting mutation was an 11-bp deletion (acacctttggt) on exon 1 that caused premature stop of FH protein. No homozygous -/- mutant was revealed in litters.
Genetic Status: Heterozygous
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21387,524,331 - 87,550,215RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01393,651,486 - 93,677,371RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01398,116,496 - 98,142,636RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41391,329,837 - 91,355,722RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Generation of TALEN-mediated FH knockout rat model. Yu D, etal., Oncotarget. 2016 Sep 20;7(38):61656-61669. doi: 10.18632/oncotarget.11429.


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-09-28 SD-Fhem1+/-    SD-Fhem1Sage+/-    Symbol updated 68687 APPROVED
2018-09-28 SD-Fhem1+/-    SD-Fhem1Sage+/-    Symbol updated 68687 APPROVED