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Strain Registration

Strain: SD-Abcc6em2Qlju+/+

Symbol: SD-Abcc6em2Qlju+/+
Strain: SD-Abcc6em2+/Abcc6em2+
Substrain: Qlju
RGD ID: 13792683
Citation ID: RRID:RGD_13792683
Ontology ID: RS:0004628
Type: mutant
Source: Thomas Jefferson University, Philadelphia
Origin: This strain was produced by injecting ZFNs into SD embryos. ZFNs were designed to target exon 1 of rat Abcc6 gene at the binding site/cutting site 5-CACGCCTGGAGAGTCCTGcgcaggCCTGAGGGTGAGTCC-3 (c.24-c.62). The resulting mutation is a 23 bp-deletion (TGCGCAGGCCTGAGGGTGAGTCC) from the first coding exon of the rat Abcc6 gene. This wild type mutant is the wild type offspring from the cross of heterozygous mutants.
Genetic Status: Wild Type
Last Known Status: Unknown





Phenotype Values via Phenominer Click to see Annotation Detail View

Related Phenotype Data for Term "SD-Abcc6em2Qlju+/+" (RS:0004628)

Rat Strains:
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References

References - curated
# Reference Title Reference Citation
1. Abcc6 Knockout Rat Model Highlights the Role of Liver in PPi Homeostasis in Pseudoxanthoma Elasticum. Li Q, etal., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19.

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