Strain Report - Rat Genome Database

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Strain: SD-Lamp2em1

Symbol: SD-Lamp2em1
Strain: SD-Lamp2em1
RGD ID: 13703119
Citation ID: RRID:RGD_13703119
Ontology ID: RS:0004603
Alleles: Lamp2em1
Type: mutant
Source: State Key Laboratory of Cancer Biology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China
Origin: This strain was produced by injecting TALEN targeting exon 2 of rat Lamp2 into SD embryos. The resulting mutation is a 2-bp deletion and results in knockout of Lamp2 protein in Lamp2 y/- male.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X117,173,097 - 117,222,090RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X124,722,628 - 124,766,079RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X124,809,053 - 124,852,509RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4X6,908,285 - 6,951,772RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Characterisation of Lamp2-deficient rats for potential new animal model of Danon disease. Ma S, etal., Sci Rep. 2018 May 2;8(1):6932. doi: 10.1038/s41598-018-24351-w.
2. A Critical Evaluation of Liver Pathology in Humans with Danon Disease and Experimental Correlates in a Rat Model of LAMP-2 Deficiency. Wang L, etal., Clin Rev Allergy Immunol. 2017 Aug;53(1):105-116. doi: 10.1007/s12016-017-8598-3.


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