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Strain: SD-Lepem1

Symbol: SD-Lepem1
Strain: SD-Lepem1
RGD ID: 13210578
Citation ID: RRID:RGD_13210578
Ontology ID: RS:0004545
Alleles: Lepem1
Also Known As: LepdeltI14/deltI14; SD-Lepem1; SD-Lep^[em1]
Type: mutant
Available Source: Not Available
Description: This CRISPR/Cas9 model possesses a 3 bp(ATC) deletion resulting in the deletion of isoleucine at position 14. The Lep mutant rats exhibited similar mutant phenotypes to Lep and Lepr null rats.
Genetic Status: Homozygous
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2457,661,127 - 57,675,262RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0456,337,695 - 56,351,818RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0456,085,079 - 56,099,209RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4455,943,837 - 55,945,938RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. The 14th Ile residue is essential for Leptin function in regulating energy homeostasis in rat. Xu S, etal., Sci Rep. 2016 Jul 5;6:28508. doi: 10.1038/srep28508.

Region


Additional Information