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Strain: F344.OLETF-(D11Rat4-D11Rat1)/Tj

Symbol: F344.OLETF-(D11Rat4-D11Rat1)/Tj
Strain: F344.OLETF-(D11Rat4-D11Rat1)
Substrain: Tj
RGD ID: 1302663
Citation ID: RRID:RGD_1302663
Ontology ID: RS:0000287
Previously known as: F.O-Nidd4/of; F344.OLETF-(D11Rat4-D11Rat1)/Tj
Type: congenic
Source: National BioResource Project for the Rat in Japan
Origin: Male OLETF was crossed with female F344. F1 were backcrossed to female F344 for 5 generations. Microsatellite-based genotyping was performed to select the best male that had the best OLETF donor genome. Once the region was fixed the resultant congenic strain was maintained by brother-sister mating.37.4 cM segment of the OLETF genome was transferred.
Inbred Generations: F10
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21162,790,342 - 82,450,994RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01165,352,097 - 86,593,596RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01166,731,054 - 89,693,367RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41164,573,222 - 84,443,333RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View
hyperglycemia  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Examination of OLETF-derived non-insulin-dependent diabetes mellitus QTL by construction of a series of congenic rats. Kose H, etal., Mamm Genome 2002 Oct;13(10):558-62.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D11Rat4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21162,790,342 - 62,790,509 (+)MAPPER
Rnor_6.01165,687,080 - 65,687,246NCBI
Rnor_6.01165,352,097 - 65,352,263NCBI
Rnor_5.01166,731,054 - 66,731,220UniSTS
RGSC_v3.41164,573,222 - 64,573,702RGD
RGSC_v3.41164,573,426 - 64,573,592UniSTS
RGSC_v3.11164,631,015 - 64,631,181RGD
Celera1162,288,965 - 62,289,117UniSTS
RH 3.4 Map11493.0UniSTS
RH 3.4 Map11493.0RGD
RH 2.0 Map11184.3RGD
SHRSP x BN Map1128.7798RGD
Cytogenetic Map11q21UniSTS

Flank 2 / 1 (D11Rat1)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,450,825 - 82,450,994 (+)MAPPER
Rnor_6.01186,593,428 - 86,593,596NCBI
Rnor_5.01189,693,199 - 89,693,367UniSTS
RGSC_v3.41184,443,164 - 84,443,333RGD
RGSC_v3.41184,443,165 - 84,443,333UniSTS
RGSC_v3.11184,483,762 - 84,483,930RGD
Celera1181,226,132 - 81,226,300UniSTS
RH 3.4 Map11703.5UniSTS
RH 3.4 Map11703.5RGD
SHRSP x BN Map1138.2299UniSTS
SHRSP x BN Map1138.2299RGD
Cytogenetic Map11q23UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics hyperglycemia after glucose challenge in the OGTT assay 625760
strain_reproduction Good breeding performance 625760

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-01-19 F344.OLETF-(D11Rat4-D11Rat1)/Tj    F344.OLETF-(D11Rat4-D11Rat1)/Tj    Name updated 68913 APPROVED