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Strain Registration

Strain: F344.OLETF-(D9Mgh8-D9Rat15)/Tj

Symbol: F344.OLETF-(D9Mgh8-D9Rat15)/Tj
Strain: F344.OLETF-(D9Mgh8-D9Rat15)
Substrain: Tj
RGD ID: 1302650
Citation ID: RRID:RGD_1302650
Ontology ID: RS:0000297
Also Known As: F.O-Nidd8/of; F344.OLETF-(D9Mgh8-D9Rat15)/Tj
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Description: Male OLETF was crossed with female F344. F1 were backcrossed to female F344 for 5 generations. Microsatellite-based genotyping was performed to select the best male that had the best OLETF donor genome. Once the region was fixed the resultant congenic strain was maintained by brother-sister mating.37.4 cM segment of the OLETF genome was transferred.
Inbred Generations: F11
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2936,840,385 - 65,383,934RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0941,139,089 - 70,686,886RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0940,808,491 - 71,887,966RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4933,374,546 - 62,634,991RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Examination of OLETF-derived non-insulin-dependent diabetes mellitus QTL by construction of a series of congenic rats. Kose H, etal., Mamm Genome 2002 Oct;13(10):558-62.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D9Mgh8)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2936,840,385 - 36,840,608 (+)MAPPER
Rnor_6.0941,139,089 - 41,139,311NCBI
Rnor_5.0940,808,491 - 40,808,713UniSTS
RGSC_v3.4933,374,546 - 33,374,769RGD
RGSC_v3.4933,374,547 - 33,374,769UniSTS
RGSC_v3.1933,375,961 - 33,376,183RGD
Celera934,625,350 - 34,625,572UniSTS
RH 3.4 Map9352.1UniSTS
RH 3.4 Map9352.1RGD
RH 2.0 Map9355.0RGD
Cytogenetic Map9q21UniSTS

Flank 2 / 1 (D9Rat15)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2965,383,789 - 65,383,934 (+)MAPPER
Rnor_6.0970,686,742 - 70,686,886NCBI
Rnor_5.0971,887,822 - 71,887,966UniSTS
RGSC_v3.4962,634,672 - 62,634,991RGD
RGSC_v3.4962,634,744 - 62,634,888UniSTS
RGSC_v3.1962,781,726 - 62,781,870RGD
Celera962,794,142 - 62,794,286UniSTS
RH 3.4 Map9551.9UniSTS
RH 3.4 Map9551.9RGD
RH 2.0 Map9613.3RGD
SHRSP x BN Map944.4198RGD
FHH x ACI Map942.29RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics hyperglycemia after glucose challenge in the OGTT assay 625760
strain_reproduction Good breeding performance 625760

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-01-19 F344.OLETF-(D9Mgh8-D9Rat15)/Tj    F344.OLETF-(D9Mgh8-D9Rat15)/Tj    Name updated 68913 APPROVED
2015-01-19 F344.OLETF-(D9Mgh8-D9Rat15)/Tj    F344.OLETF-(D9Mgh8-D9Rat15)/Tj    Name updated 68913 APPROVED