Strain Report - Rat Genome Database

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Strain: LEC/Hok

Symbol: LEC/Hok
Strain: LEC
Substrain: Hok
Full Name: Long Evans Cinnamon
RGD ID: 1302648
Citation ID: RRID:RGD_1302648
Ontology ID: RS:0000446
Alleles: Atp7bhts
Also known as: NBRP Rat No: 0042; LEC; MDC-01-78
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: At the Center for Experimental Plants and Animals, Hokkaido University, LEC, along with LEA, was established from a closed colony of Long-Evans rats obtained from Kobe University in 1975. In 1984, within the LEC rats of their F24 generation, a rat exhibiting spontaneous hepatitis with severe jaundice was found (Yoshida, 1987). The LEC was available from Charles River Japan, Inc., Kanagawa, as of spring, 1991.
Inbred Generations: F94
Last Known Status: Unknown (as of 2016-12-01)
Research Usage Cancer; Immunology
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21669,952,286 - 70,024,404RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01674,865,516 - 74,944,935RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01674,495,179 - 74,575,822RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41674,607,988 - 74,680,080RGD_MAPPER_PIPELINERGSC3.4





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Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
timed urine volume
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
liver copper weight to liver wet weight ratio
liver copper weight to liver dry weight ratio
urine sodium excretion rate to body weight ratio
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
plasma total bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio
serum copper level

References


Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Carries a mutation causing fulminant hepatitis and jaundice at about four months of age. 1302497
strain_other A model of Wilson disease. 1302497

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-07 LEC/Hok  Long Evans Cinnamon  LEC/Hok  Long Evans Cinnamon  Name updated 68913 APPROVED