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Clinical Measurements:
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Options: | View chart | | | Download data table | | | View expanded data table |
# | Reference Title | Reference Citation |
1. | Exaggerated response to restraint stress in rats congenic for the chromosome 1 blood pressure quantitative trait locus. | Cui ZH, etal., Clin Exp Pharmacol Physiol 2003 Jul;30(7):464-9. |
2. | Exaggerated response to cold stress in a congenic strain for the quantitative trait locus for blood pressure. | Cui ZH, etal., J Hypertens 2004 Nov;22(11):2103-9. |
3. | Relation of Blood Pressure Quantitative Trait Locus on Rat Chromosome 1 to Hyperactivity of Rostralventrolateral Medulla. | Iigaya K, etal., Hypertension. 2008 Dec 1. |
4. | Strains registered by the National Bio Resource Project for the Rat in Japan | Personal Communication with NBRP |
5. | RGD Strain RSO annotation pipeline | RGD Automated Pipelines |
6. | Enhanced sympathetic control of renal function in rats congenic for the hypertension-related region on chromosome 1. | Wang T, etal., Clin Exp Pharmacol Physiol. 2005 Dec;32(12):1055-60. |
7. | SYMPATHETIC REGULATION OF RENAL FUNCTION IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS CONGENIC FOR CHROMOSOME 1 BLOOD PRESSURE QUANTITATIVE TRAIT LOCI. | Wang T, etal., Clin Exp Pharmacol Physiol. 2008 Jun 18;. |
8. | Sympathetic regulation of the renal functions in rats reciprocally congenic for chromosome 1 blood pressure quantitative trait locus. | Wang T, etal., Hypertens Res. 2008 Mar;31(3):561-8. |
9. | A 1.8-Mbp fragment on chromosome 1 affects sympathetic response to stress: evaluation in reciprocal congenic strains between stroke-prone spontaneously hypertensive rat and Wistar-Kyoto rat. | Xiao B, etal., J Hypertens. 2010 Nov 8. |
10. | Sympathetic hyperreactivity to air-jet stress in the chromosome 1 blood pressure quantitative trait locus congenic rats. | Yamazato M, etal., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
11. | Congenic removal of a QTL for blood pressure attenuates infarct size produced by middle cerebral artery occlusion in hypertensive rats. | Yao H, etal., Physiol Genomics. 2007 Feb 27;. |
Flank 1 / 1 (D1Wox29) |
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Flank 2 / 1 (D1Arb21) |
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Symbol | Name | Trait |
Cstrr1 | Cold stress response QTL 1 |
catecholamine amount (VT:0010543)
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Stresp23 | Stress response QTL 23 |
kidney sympathetic nerve activity (VT:0004050)
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Note Type | Note | Reference |
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strain_phys_biochem | displays increased urinary excretion of norepinephrine (NE) and vanillylmandelic acid, increased plasma NE levels, and increased blood pressure in response to cold stress at levels greater than those observed in the parental WKY strain under cold stress | 1302892 |
strain_phys_biochem | After air-jet stress shows a significant increase in renal sympathetic nerve activity and mean arterial pressure compared with WKY strain. | 1578503 |
strain_phys_biochem | Basal membrane potential of rostral ventrolateral medulla (RVLM) neurons was less than that of WKY/Izm | 2302408 |
strain_phys_biochem | Depolarization of RVLM neurons in response to angiotensin II was larger than that of WKY/Izm | 2302408 |
strain_phys_biochem | significant increase in urinary norepinephrine, vanillylmandelic acid, and blood pressure compared to WKY animals was observed | 1302892 |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2012-05-10 | WKY.SHRSP-(D1Wox29-D1Arb21)/Izm | WKY.SHRSP-(D1Wox29-D1Arb21)/Izm | Name updated | 68913 | APPROVED | ||
2012-05-10 | WKY.SHRSP-(D1Wox29-D1Arb21)/Izm | WKY.SHRSP-(D1Wox29-D1Arb21)/Izm | Name updated | 68913 | APPROVED |