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Strain Registration

Strain: F344.OLETF-(D12Rat8-D12Rat16)/Tj

Symbol: F344.OLETF-(D12Rat8-D12Rat16)/Tj
Strain: F344.OLETF-(D12Rat8-D12Rat16)
Substrain: Tj
RGD ID: 1302635
Citation ID: RRID:RGD_1302635
Ontology ID: RS:0000288
Also Known As: F.O-Nidd9/of; F344.OLETF-(D12Rat8-D12Rat16)/Tj
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Description: Male OLETF was crossed with female F344. F1 were backcrossed to female F344 for 5 generations. Microsatellite-based genotyping was performed to select the best male that had the best OLETF donor genome. Once the region was fixed the resultant congenic strain was maintained by brother-sister mating.37.4 cM segment of the OLETF genome was transferred.
Inbred Generations: F11
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21222,779,459 - 30,427,275RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01225,799,119 - 34,265,075RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01227,805,580 - 36,160,041RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41223,934,730 - 31,489,223RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Examination of OLETF-derived non-insulin-dependent diabetes mellitus QTL by construction of a series of congenic rats. Kose H, etal., Mamm Genome 2002 Oct;13(10):558-62.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D12Rat8)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21222,779,459 - 22,779,600 (+)MAPPER
Rnor_6.01225,799,119 - 25,799,259NCBI
Rnor_5.01227,805,580 - 27,805,720UniSTS
RGSC_v3.41223,934,730 - 23,934,871RGD
RGSC_v3.41223,934,731 - 23,934,871UniSTS
RGSC_v3.11223,797,947 - 23,798,087RGD
Celera1224,537,472 - 24,537,612UniSTS
RH 3.4 Map12356.3UniSTS
RH 3.4 Map12356.3RGD
RH 2.0 Map12249.4RGD
SHRSP x BN Map1226.09RGD
FHH x ACI Map1211.22RGD

Flank 2 / 1 (D12Rat16)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21230,427,103 - 30,427,275 (+)MAPPER
Rnor_6.01234,264,906 - 34,265,075NCBI
Rnor_5.01236,159,872 - 36,160,041UniSTS
RGSC_v3.41231,489,054 - 31,489,223UniSTS
RGSC_v3.41231,489,053 - 31,489,223RGD
RGSC_v3.11231,352,442 - 31,352,611RGD
Celera1232,106,503 - 32,106,672UniSTS
RH 3.4 Map12490.6RGD
RH 3.4 Map12490.6UniSTS
RH 2.0 Map12360.5RGD
SHRSP x BN Map1238.78RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics hyperglycemia after glucose challenge in the OGTT assay 625760
strain_reproduction Good breeding performance 625760

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-01-19 F344.OLETF-(D12Rat8-D12Rat16)/Tj    F344.OLETF-(D12Rat8-D12Rat16)/Tj    Name updated 68913 APPROVED
2015-01-19 F344.OLETF-(D12Rat8-D12Rat16)/Tj    F344.OLETF-(D12Rat8-D12Rat16)/Tj    Name updated 68913 APPROVED