Strain Report - Rat Genome Database

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Strain: SD-Tg(Th-Ghsros)

Symbol: SD-Tg(Th-Ghsros)
Strain: SD-Tg(Th-Ghsros)
RGD ID: 12910127
Citation ID: RRID:RGD_12910127
Ontology ID: RS:0004462
Alleles: Ghsr
Also Known As: GHS-R transgene line 9-4
Type: transgenic
Available Source: Not Available
Description: This transgenic strain carries a synthetic 108-nucleotide DNA fragment spanning the 5 prime extracellular region of GHS-R was cloned in the antisense orientation driven by tyrosine hydroxylase (Th) promoter.
Genetic Status: Homozygous
Coat Color: Albino
Last Known Status: Unknown

Phenotype Annotations     Click to see Annotation Detail View


References - curated
# Reference Title Reference Citation
1. DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype. Banerjee SA, etal., Brain Res Mol Brain Res. 1994 Jul;24(1-4):89-106.
2. Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity. Shuto Y, etal., J Clin Invest 2002 Jun;109(11):1429-36.


Additional Information