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Strain: ZDF-Leprfa/Drt

Symbol: ZDF-Leprfa/Drt
Strain: ZDF-Leprfa
Substrain: Drt
Full Name: Zucker Diabetic Fatty Rat
RGD ID: 12859287
Citation ID: RRID:RGD_12859287
Ontology ID: RS:0004405
Alleles: Lepr
Also Known As: ZDF-Leprfa/Drt; ZDF-Lepr^[fa]/Drt
Type: inbred
Available Source: Not Available
Origination: Indiana University School of Medicine, Indianapolis.
Description: "Zucker" fatty rats of undefined outbred background, inbred with selection for non-insulin-dependent diabetes mellitus by mating diabetic homozygous fatty males to heterozygous sisters.
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide. Alemzadeh R and Tushaus KM, Endocrinology 2004 Dec;145(12):5476-84. Epub 2004 Aug 19.
2. Zucker Diabetic Fatty Rat as a Model for Non-insulin-dependent Diabetes Mellitus Richard G. Peterson, Walter N. Shaw, Mary-Ann Neel, Leah A. Little, J. Eichberg, ILAR news1990:32(3)16-19


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-14 ZDF-Leprfa/Drt  Zucker Diabetic Fatty Rat  ZDFfa/Drt  Zucker Diabetic Fatty Rat  Symbol updated 68687 APPROVED