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Strain Registration

Strain: SD-Ubdem1

Symbol: SD-Ubdem1
Strain: SD-Ubdem1
RGD ID: 126925138
Citation ID: RRID:RGD_126925138
Ontology ID: RS:0004941
Alleles: Ubdem1
Previously known as: FAT10-KO
Type: mutant
Source: Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006
Origin: This Ubd (FAT10) knockout rat strain was generated using theCRISPR-Cas9 technique in a Sprague Dawley (SD) background. The knockout allele has a 911 bp deletion of exon 2, leading to a truncated protein of Ubd.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,385,487 - 1,387,438RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0201,876,175 - 1,878,126RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0203,917,777 - 3,919,728RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4201,475,944 - 1,477,895RGD_MAPPER_PIPELINERGSC3.4





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. FAT10 attenuates hypoxia-induced cardiomyocyte apoptosis by stabilizing caveolin-3. Zhou Q, etal., J Mol Cell Cardiol. 2018 Mar;116:115-124. doi: 10.1016/j.yjmcc.2018.02.008. Epub 2018 Feb 10.

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