Strain Report - Rat Genome Database

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Strain: DA-Csf1rtm(EGFP)-/-/Hume

Symbol: DA-Csf1rtm(EGFP)-/-/Hume
Strain: DA-Csf1rtm(EGFP)-/-
Substrain: Hume
RGD ID: 126779592
Citation ID: RRID:RGD_126779592
Ontology ID: RS:0004906
Alleles: Csf1rtm(EGFP)Tset
Also Known As: DA-Csf1r^[tm(EGFP)-/-]/Hume
Type: mutant
Available Source: Not Available
Origination: Department of Microbiology, University of Queensland, Brisbane, Queensland 4072 Australia
Description: Heterozygotes "SD-Csf1rtm(EGFP)+/-/Tset" were back-crossed for at least 7 generations to the inbred dark agouti (DA) background from the Animal Resource Centre, Western Australia. The homozygotes were obtained by crossing of heterozygotes
Genetic Status: Homozygous
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21854,546,673 - 54,590,418RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01856,414,493 - 56,458,300RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01855,662,670 - 55,689,297RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41857,080,324 - 57,107,295RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations. Patkar OL, etal., Neurobiol Dis. 2021 Apr;151:105268. doi: 10.1016/j.nbd.2021.105268. Epub 2021 Jan 12.


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-04-13 DA-Csf1rtm(EGFP)-/-/Hume    DA-Csf1rtm(EGFP)+/+/Hume    Symbol and/or name change 68913 APPROVED