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Strain: iNP-Npyem6Sage+/-/Iusm

Symbol: iNP-Npyem6Sage+/-/Iusm
Strain: iNP-Npyem6Sage+/-
Substrain: Iusm
RGD ID: 11531104
Citation ID: RRID:RGD_11531104
Ontology ID: RS:0004215
Alleles: Npyem6Sage
Also Known As: Npy+/-; NP/Iusm-Npyem6Sage+/- ; NP-Npyem6Sage+/-/Iusm; NP/Iusm-Npyem6Sage+/-; iNP-Npy^[em6Sage+/-]/Iusm
Type: mutant
Available Source: Not Available
Origination: Department of Gastroenterology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Description: The heterozygous ZFN mutant rats were produced by backcrossing mutant founders with iNP/Iusm. Genotyping of the offspring was carried out by PCR amplification of a 26-bp deleted fragment, including 6 bp in intron 1 and 20 bp in exon 2.
Genetic Status: Heterozygous
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,881,294 - 78,888,495RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0479,557,856 - 79,565,059RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04144,233,753 - 144,240,956RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4478,038,013 - 78,045,187RGD_MAPPER_PIPELINERGSC3.4





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. A novel F8 -/- rat as a translational model of human hemophilia A. Nielsen LN, etal., J Thromb Haemost. 2014 Aug;12(8):1274-82. doi: 10.1111/jth.12635.
2. Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight. Qiu B, etal., J Genet Genomics. 2016 Jul 20;43(7):421-30. doi: 10.1016/j.jgg.2016.04.010. Epub 2016 Apr 29.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 iNP-Npyem6Sage+/-/Iusm    NP-Npyem6Sage+/-/Iusm    Symbol and/or name change 68913 APPROVED
2023-04-28 NP-Npyem6Sage+/-/Iusm    NP/Iusm-Npyem6Sage+/-    Symbol and/or name change 68913 APPROVED
2018-03-14 NP/Iusm-Npyem6Sage+/-    NP/Iusm-Npyem6Sage+/-     Symbol updated 68687 APPROVED
2018-03-14 NP/Iusm-Npyem6Sage+/-    NP/Iusm-Npyem6Sage+/-     Symbol updated 68687 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage+/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage+/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage+/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage+/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage+/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage+/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage +/-    Symbol updated 68687 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage +/-    Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage +/-    Symbol updated 68687 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage+/-     NP/Iusm-Npyem6Sage +/-    Name updated 68913 APPROVED