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Strain: SD-Il15em1Soar

Symbol: SD-Il15em1Soar
Strain: SD-Il15em1
Substrain: Soar
RGD ID: 11087551
Citation ID: RRID:RRRC_00769
Ontology ID: RS:0004194
Alleles: Il15em1Soar;   Il15
Also Known As: Il15-d7(E2); SD-Il15em1Soar; SD-Il15^[em1Soar]
Type: mutant
Available Source: Rat Resource and Research Center
Origination: University of Kansas Medical Center
Description: Zinc finger nuclease mediated 7bp deletion within exon 2 of the Il15 gene, resulting in a frameshift and premature stop codon.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21925,696,013 - 25,696,019RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01923,553,406 - 23,553,412RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01934,532,033 - 34,598,725RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41927,487,268 - 27,498,973RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
2. A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats. Qaisar N, etal., Diabetes. 2017 Jan;66(1):145-157. doi: 10.2337/db16-0462. Epub 2016 Oct 7.
3. Natural killer-cell deficiency alters placental development in rats. Renaud SJ, etal., Biol Reprod. 2017 Jan 1;96(1):145-158. doi: 10.1095/biolreprod.116.142752.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Il15em1Soar-var1 chr19 25696013 25696019 CTTAACT - deletion mRatBN7.2
Il15em1Soar-var1 chr19 23553406 23553412 CTTAACT - deletion Rnor_6.0

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other Investigating in vivo interleukin 15 cytokine biology and the consequences of natural killer cell deficiencies 2292495
Database Acc Id Source(s)
RRRC RRRC:00769 RGD