Strain Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Strain Registration

Strain: F344-AsipATyrCKitH/Kyo

Symbol: F344-AsipATyrCKitH/Kyo
Strain: F344-AsipATyrCKitH
Substrain: Kyo
RGD ID: 11040974
Citation ID: RRID:RGD_11040974
Ontology ID: RS:0004158
Alleles: Asip;   Tyr;   Kit
Also Known As: Agouti Fischer; NBRP Rat No: 0769; F344-AsipATyrCKitH/Kyo; F344-Asip^[A]Tyr^[C]Kit^[H]/Kyo
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: 1) point mutation in the exon 2 of Tyrosinase (Tyr) gene (albino phenotype), 2) 19-bp deletion in Asip gene (Agouti phenotype), and 3) retrotransposon insertion (7-bp) in kit gene (hooded phenotype) were targeted by CRISPR/Cas9 system using ssODN. The rat coat colour phenotype was changed from white to Agouti. Background strain: F344/Stm
Last Known Status: Live Animals; Cryopreserved Sperm
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23143,473,584 - 143,561,170RGD_MAPPER_PIPELINEmRatBN7.2
mRatBN7.21432,547,459 - 32,624,694RGD_MAPPER_PIPELINEmRatBN7.2
mRatBN7.21141,115,036 - 141,210,207RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.03150,492,010 - 150,579,870RGD_MAPPER_PIPELINERnor6.0
Rnor_6.01435,072,131 - 35,149,638RGD_MAPPER_PIPELINERnor6.0
Rnor_6.01151,012,598 - 151,106,802RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01434,901,860 - 34,979,384RGD_MAPPER_PIPELINERnor5.0
Rnor_5.01157,322,968 - 157,416,594RGD_MAPPER_PIPELINERnor5.0
Rnor_5.03156,860,395 - 156,949,277RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.43145,445,175 - 145,536,831RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.41434,906,043 - 34,984,819RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.41143,641,257 - 143,746,315RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform. Yoshimi K, etal., Nat Commun. 2014 Jun 26;5:4240. doi: 10.1038/ncomms5240.

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Agouti coat colour (genetic background: F344/Stm) 1302502
strain_reproduction homozygous condition (wild-type color: Agouti) 1302502