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Strain Registration

Strain: LEA.F344-(D20Rat47-D20Mgh4)/Tj

Symbol: LEA.F344-(D20Rat47-D20Mgh4)/Tj
Strain: LEA.F344-(D20Rat47-D20Mgh4)
Substrain: Tj
RGD ID: 10045590
Citation ID: RRID:RGD_10045590
Ontology ID: RS:0003929
Also Known As: LEA.F344-(D20Rat47-D20Mgh4)/Tj; NBRP Rat No: 0754
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Long-Evans Agouti (LEA), type 2 diabetes model, dies from lymphocytic insulitis induced by radiation (4 Gy). This LEA.F344-(D20Rat47-D20Mgh4) strain is a congenic strain made by introducing a segment of chromosome 20 (D20Rat47-D20Mgh4) from F344 strain into LEA strain.
Coat Color: Agouti
Inbred Generations: F15
Last Known Status: Cryopreserved Sperm
Research Usage Diabetes Obesity
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8201,533,083 - 6,693,431RGD_MAPPER_PIPELINE
mRatBN7.2201,527,842 - 6,691,706RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0202,018,654 - 5,875,448RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.0204,059,279 - 7,910,747RGD_MAPPER_PIPELINERnor_5.0
RGSC_v3.4201,616,332 - 6,880,472RGD_MAPPER_PIPELINERGSC_v3.4






References

References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D20Rat47)
Rat AssemblyChrPosition (strand)Source
GRCr8201,533,083 - 1,533,200 (+)Marker Load Pipeline
mRatBN7.2201,527,842 - 1,527,959 (+)MAPPER
Rnor_6.0202,018,654 - 2,018,770NCBI
Rnor_5.0204,059,279 - 4,059,395UniSTS
RGSC_v3.4201,616,332 - 1,616,449RGD
RGSC_v3.4201,616,333 - 1,616,449UniSTS
Celera202,236,388 - 2,236,504UniSTS
RGSC_v3.1201,616,333 - 1,616,449RGD
RH 3.4 Map2015.8UniSTS
RH 3.4 Map2015.8RGD
RH 2.0 Map200.0RGD
SHRSP x BN Map200.0RGD
Cytogenetic Map20p12UniSTS

Flank 2 / 1 (D20Mgh4)
Rat AssemblyChrPosition (strand)Source
GRCr8206,693,321 - 6,693,431 (+)Marker Load Pipeline
mRatBN7.2206,691,596 - 6,691,706 (+)MAPPER
Rnor_6.0205,875,339 - 5,875,448NCBI
Rnor_5.0207,910,638 - 7,910,747UniSTS
RGSC_v3.4206,880,362 - 6,880,471RGD
RGSC_v3.4206,880,363 - 6,880,472UniSTS
Celera208,247,548 - 8,247,657UniSTS
RGSC_v3.1206,880,589 - 6,880,698RGD
RH 3.4 Map2077.5UniSTS
RH 3.4 Map2077.5RGD
RH 2.0 Map2097.1RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics This rat strain develops type 2 diabetes. However, lymphocytic insulitis is not induced by X-ray radiation. 1302502
strain_reproduction Mating between male and female rat 1302502