Strain Report - Rat Genome Database

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Strain: WN/N

Symbol: WN/N
Strain: WN
Substrain: N
Full Name: Inbred Wistar; W/N
RGD ID: 10045
Citation ID: RRID:RGD_10045
Ontology ID: RS:0001082
Also Known As: MDC-04-46
Type: inbred
Available Source: Not Available
Origination: NIH Animal Genetic Resource
Description: Heston in 1942 from Wistar stock of Nettleship, to National Institutes of Health in 1950 at F15.
Genetic Markers: c
Coat Color: Albino,
Inbred Generations: F105
Last Known Status: Unknown





Phenotype Values via Phenominer Click to see Annotation Detail View

Related Phenotype Data for Term "WN/N" (RS:0001082)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Inbred Strains Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
2. Update to previous Strain Data Festing, MFW, Personal Communication Update, Feb-2000
3. NIH Rat Strain Data NIH Rat Strain Data
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines
5. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.

Region

Strain Samples in RGD with Damaging Variants (Polyphen)
AssemblySample 
RGSC_v3.4 WN/N (KNAW) View Damaging Variants
Rnor_5.0 WN/N (KNAW) View Damaging Variants
Rnor_6.0 WN/N (MCW) View Damaging Variants
Rnor_6.0 WN/N (2020) View Damaging Variants
mRatBN7.2 WN/N (2020) View Damaging Variants


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Anterior pituitary tumours nearly 100% in females over 18 months of age, pheochromocytomas orpreneoplastic nodules in adrenal medulla about 40% in males, granulocytic leukaemia 14% in animals over 18 months of age. Rarely show hyperplastic cortical nodules or adrenal cortical adenomas. High incidence of severe chronic nephritis. (Snell 1967). High 10-week body weight in males (19/23) (Tanase et al 1982). High relative heart weight in 10-week old males (19/23)(Tanase et al 1982). 1004
strain_life_disease Anterior pituitary tumours nearly 100% in females over 18 months of age, pheochromocytomas orpreneoplastic nodules in adrenal medulla about 40% in males, granulocytic leukaemia 14% in animals over 18 months of age. Rarely show hyperplastic cortical nodules or adrenal cortical adenomas. High incidence of severe chronic nephritis. (Snell 1967). High 10-week body weight in males (19/23) (Tanase et al 1982). High relative heart weight in 10-week old males (19/23)(Tanase et al 1982). 634612