Strain Report - Rat Genome Database

Name: BBDP.ACI-( D2Arb16-D2Rat63 )/Sunn
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: BBDP.ACI-(D2Arb16-D2Rat63)/Sunn

Symbol:

BBDP.ACI-(D2Arb16-D2Rat63)/Sunn

Strain:

BBDP.ACI-(D2Arb16-D2Rat63)

Substrain:

Sunn

RGD ID:

10043129

Citation ID:

RRID:RGD_10043129

Ontology ID:

RS:0003902

Previously known as:

BBDP.ACI-(D2Arb16-D2Rat63)/Sunn; 2BAa

Type:

congenic

Source:

Sunnybrook Research Institute, Toronto, Ontario, Canada

Origin:

104 Mb region from ACI.BBDP-(RT1^u),(Gimap5)/Sunn is introgressed into the BBDP/WorSunn background which carries the centromeric region of Iddm33 and telomeric region of Iddm26

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	190,602,746 - 222,436,696	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	2	205,572,952 - 239,166,203	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	2	225,003,539 - 257,699,856	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	2	198,312,439 - 231,465,091	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number (IAGP)

decreased IgE level (IAGP)

decreased susceptibility to autoimmune diabetes (IAGP)

increased macrophage cell number (IAGP)

thymus hypoplasia (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines
2.	Genetic dissection of Iddm26 in the spontaneously diabetic BBDP rat.	Sarmiento J, etal., Genes Immun. 2014 Sep;15(6):378-91. doi: 10.1038/gene.2014.29. Epub 2014 Jun 12.

Region

Position Markers

Flank 1 / 1 (D2Arb16)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	190,602,746 - 190,602,963 (+)	MAPPER
Rnor_6.0	2	205,572,952 - 205,573,168	NCBI
Rnor_5.0	2	225,003,539 - 225,003,755	UniSTS
RGSC_v3.4	2	198,312,439 - 198,312,656	RGD
RGSC_v3.4	2	198,312,440 - 198,312,656	UniSTS
RGSC_v3.1	2	198,275,193 - 198,275,410	RGD
Celera	2	183,076,093 - 183,076,309	UniSTS
SHRSP x BN Map	2	72.7698	UniSTS
SHRSP x BN Map	2	72.7698	RGD
Cytogenetic Map	2	q34	UniSTS

Flank 2 / 1 (D2Rat63)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	222,436,573 - 222,436,696 (+)	MAPPER
Rnor_6.0	2	239,166,081 - 239,166,203	NCBI
Rnor_5.0	2	257,699,734 - 257,699,856	UniSTS
RGSC_v3.4	2	231,464,968 - 231,465,091	RGD
RGSC_v3.4	2	231,464,969 - 231,465,091	UniSTS
RGSC_v3.1	2	231,451,708 - 231,451,831	RGD
Celera	2	214,666,794 - 214,666,916	UniSTS
RH 2.0 Map	2	1115.0	RGD
SHRSP x BN Map	2	94.3198	RGD
FHH x ACI Map	2	106.9199	RGD

Strain QTL Data

Symbol	Name	Trait
Iddm55	Insulin dependent diabetes mellitus QTL 55	blood glucose amount (VT:0000188)

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_characteristics	mean age of onset is 84.2 days as compared to BBDP is 80.8 days	10043114

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: BBDP.ACI-(D2Arb16-D2Rat63)/Sunn

Mammalian Phenotype