Strain Report - Rat Genome Database

Name: MNS/Gib
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain: MNS/Gib
Symbol:	MNS/Gib
Strain:	MNS
Substrain:	Gib
Full Name:	Milan Normotensive Strain
RGD ID:	10028
RRID:	RGD_10028
Ontology ID:	RS:0000581
Also known as:	MDC-03-67
Type:	inbred
Source:	Department of Sciences and Biomedical Technologies, University of Milan, Milan, Italy
Origin:	Outbred Wistar rats with brother x sister mating and selection for low systolic blood pressure as a normotensive control for MHS.
Last Known Status:	Unknown

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Mammalian Phenotype

Phenotype Values via PhenoMiner Click to see Annotation Detail View

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Clinical Measurement

References

References - curated


1.	Bender K, etal., J Exp Anim Sci 1994 Aug;36(4-5):151-65.
2.	Bonne A, etal., Mol Biol Rep 2003 Sep;30(3):173-6.
3.	Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
4.	Festing, MFW, Personal Communication Update, Feb-2000
5.	Gmaj P, etal., Biochim Biophys Acta. 1988 Jun 22;941(2):187-97. doi: 10.1016/0005-2736(88)90179-4.
6.	Heeley RP, etal., Mamm Genome 1998 Mar;9(3):198-203.
7.	Institute for Animal Experimentation University of Tokushima School of Medicine
8.	Otsen M, etal., Mamm Genome 1995 Sep;6(9):595-601.
9.	RGD Automated Pipelines
10.	Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
11.	Smits BM, etal., Genome Res. 2004 Jul;14(7):1285-90.
12.	Soldati LP, etal., Lab Anim 1995 Oct;29(4):420-6.
13.	Zagato L, etal., Hypertension 2000 Nov;36(5):734-9.

Region

Strain QTL Data

Symbol	Name	Trait
Bp57	Blood pressure QTL 57	arterial blood pressure trait (VT:2000000)
Bp58	Blood pressure QTL 58	arterial blood pressure trait (VT:2000000)
Bp59	Blood pressure QTL 59	arterial blood pressure trait (VT:2000000)
Bp60	Blood pressure QTL 60	arterial blood pressure trait (VT:2000000)

Damaging Variants

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_life_disease	Have normal systolic blood pressure.	1357950
strain_phys_biochem	This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203.	737878

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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