Strain Report - Rat Genome Database
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Strain: MNR/N

Symbol: MNR/N
Strain: MNR
Substrain: N
Full Name: Maudsely non-reactive
RGD ID: 10026
RRID: RGD_10026
Ontology ID: RS:0000583
Also known as: RRRC:00174
Type: inbred
Source: NIH Animal Genetic Resource
Origin: To N 1964 at F18+? from Maas. Developed by Broadhurst, 1954, from a commercial stock, with selection for low defecation response in an open field. A number of parallel sublines are in existence; these differ at least at the agouti and the major histocompatibility loci.
Genetic Markers: A,B,c,h.
Coat Color: Albino.
Inbred Generations: F79+?.
Last Known Status: Extinct






References


Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_behavior The strain is widely used in behaviour research, and characteristics have been described by Harrington (1971a,b, 1972, 1979a-i). Long latency to emerge into a familiar (11/12) and novel (12/12) environment in females (Harrington 1971a). Low open field defecation (12/12 males, 11/12 to 9/12 depending on subline in females) (Harrington 1972). High wheel activity (1/12) (Harrington 1971b). Low open-field defecation (8/8) in hybrid offspring (Rick and Fulker 1972). 1004
strain_behavior The strain is widely used in behaviour research, and characteristics have been described by Harrington (1971a,b, 1972, 1979a-i). Long latency to emerge into a familiar (11/12) and novel (12/12) environment in females (Harrington 1971a). Low open field defecation (12/12 males, 11/12 to 9/12 depending on subline in females) (Harrington 1972). High wheel activity (1/12) (Harrington 1971b). Low open-field defecation (8/8) in hybrid offspring (Rick and Fulker 1972). 634612
strain_characteristics Other papers comparing MR and MNR or MR and MNRA include Commissaris et al (1992), Abel et al, (1992), Sara et al, (1993), Buda et al, (1994), Sara et al, (1994), Verbanac et al, (1993) 1004
strain_characteristics Other papers comparing MR and MNR or MR and MNRA include Commissaris et al (1992), Abel et al, (1992), Sara et al, (1993), Buda et al, (1994), Sara et al, (1994), Verbanac et al, (1993) 634612
strain_phys_biochem Low blood pressure (23/23), reaching 118_1.1 (SEM) mmHg at 10 weeks of age (Tanase et al 1982). Low 10-week body weight in males (1/23) (Tanase et al 1982). 1004
strain_phys_biochem Low blood pressure (23/23), reaching 118_1.1 (SEM) mmHg at 10 weeks of age (Tanase et al 1982). Low 10-week body weight in males (1/23) (Tanase et al 1982). 634612
strain_reproduction Good breeding performance (3/12) and large litter size (3/12) (Hansen et al 1973). See also MR. An extensive review of the differences between MR and MNR is given by Broadhurst (1975). 1004
strain_reproduction Good breeding performance (3/12) and large litter size (3/12) (Hansen et al 1973). See also MR. An extensive review of the differences between MR and MNR is given by Broadhurst (1975). 634612