Strain Report - Rat Genome Database
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Strain: MHS/Gib

Symbol: MHS/Gib
Strain: MHS
Substrain: Gib
Full Name: Milan Hypertensive Strain
RGD ID: 10025
RRID: RGD_10025
Ontology ID: RS:0000578
Also known as: MDC-03-44
Type: inbred
Source: Department of Sciences and Biomedical Technologies, University of Milan, Milan, Italy
Origin: Outbred Wistar rats with brother x sister mating and selection for high systolic blood pressure
Last Known Status: Unknown

Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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Strain QTL Data
Symbol Name Trait
Bp57 Blood pressure QTL 57 arterial blood pressure trait   (VT:2000000)    
Bp58 Blood pressure QTL 58 arterial blood pressure trait   (VT:2000000)    
Bp59 Blood pressure QTL 59 arterial blood pressure trait   (VT:2000000)    
Bp60 Blood pressure QTL 60 arterial blood pressure trait   (VT:2000000)    
Damaging Variants
Number of Damaging Variants
MHS/Gib (ICL) 676
MHS/Gib (KNAW) 774
MHS/Gib (RGD) 1061

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Have elevated blood pressure after 2 months of age 1357950
strain_phys_biochem This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203. 737878
strain_phys_biochem Lower inhibition of calpain by calpastain is observed in erythrocytes and kidney cells. 1357950