Strain Report - Rat Genome Database
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Strain: LOU/CHan

Symbol: LOU/CHan
Strain: LOU
Substrain: CHan
Full Name: Louvain
RGD ID: 10023
RRID: RGD_10023
Ontology ID: RS:0000562
Also known as: MDC-03-66
Type: inbred
Source: unknown
Origin: unknown
Coat Color: Albino
Inbred Generations: At Han (1989),F32.
Last Known Status: Unknown






References


Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Develop spontaneous plasmacytomas after about 8 months of age, with an incidence of about 30% in males and 16% in females. These develop rapidly, and may be detected by palpation. They usually develop in the ileocoecal lymph nodes, and about 60% of them synthesise monoclonal immunoglobulins (Bence-Jones proteins) of IgG1 (35%), IgE (36%) or IgA classes. Surgical removal of ileocaecal lymph nodes decreases plasmacytoma incidence to less than 2% (Moriame et al 1977). Ultrastructure of the tumours described by Burtonboy et al (1978). Tumours are transplantable in solid or ascites form, and retain their secretory properties through successive passages (Bazin et al 1972, Bazin et al 1973, Bazin 1974, Bazin et al 1974a,b, Beckers and Bazin 1978). More than 800 transplantable immunocytomas are now available. 1004
strain_life_disease Develop spontaneous plasmacytomas after about 8 months of age, with an incidence of about 30% in males and 16% in females. These develop rapidly, and may be detected by palpation. They usually develop in the ileocoecal lymph nodes, and about 60% of them synthesise monoclonal immunoglobulins (Bence-Jones proteins) of IgG1 (35%), IgE (36%) or IgA classes. Surgical removal of ileocaecal lymph nodes decreases plasmacytoma incidence to less than 2% (Moriame et al 1977). Ultrastructure of the tumours described by Burtonboy et al (1978). Tumours are transplantable in solid or ascites form, and retain their secretory properties through successive passages (Bazin et al 1972, Bazin et al 1973, Bazin 1974, Bazin et al 1974a,b, Beckers and Bazin 1978). More than 800 transplantable immunocytomas are now available. 634612
strain_phys_biochem This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203. 737878