Strain Report - Rat Genome Database
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Strain: IS/Kyo

Symbol: IS/Kyo
Strain: IS
Substrain: Kyo
Full Name: ishibashi rat
RGD ID: 10018
RRID: RGD_10018
Ontology ID: RS:0000410
Also known as: NBRP Rat No: 0008; MDC-02-12
Type: inbred
Source: National BioResource Project for the Rat in Japan
Origin: Ishibashi rat is derived from a cross between a wild male and a Wistar female, with sib mating since 1975 at Azabu University, transferred to Kyoto University in 1978.
Coat Color: agouti A,B,C
Inbred Generations: F20
Last Known Status: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm
Research Usage Osteosis





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via Phenominer     Click to see Annotation Detail View
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Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
activated partial thromboplastin time
prothrombin time
timed urine volume
mean corpuscular hemoglobin level
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
urine sodium excretion rate to body weight ratio
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
total plasma bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio

References


Region

Damaging Variants
Number of Damaging Variants
SampleRnor_6.0Rnor_5.0RGSC_v3.4
IS/Kyo (KyushuU) 1645


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Malformations of the thoracicolumbar vertebrae leading to kyphoscoliosis with restricted spinal canals and compressed spinal cords. The malformations occur from the 12th thoracic to the 6th lumbar vertebrae. Up to 7 vertebrae are affected, and some degree of abnormality occurs in 90% of individuals. 1302444
strain_reproduction Good breeding performance. 1302444