Strain Report - Rat Genome Database
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Strain: BBDR/Rhw

Symbol: BBDR/Rhw
Strain: BBDR
Substrain: Rhw
RGD ID: 10003
RRID: RGD_10003
Ontology ID: RS:0000073
Type: inbred
Source: R. H. William Laboratory, University of Washington, Seattle, Washington
Origin: S. Bieg and coworkers (1998) generated a congenic line in which diabetes and lymphopenia are controlled solely by Iddm 1. This strain was generated by nine cycles of cross-intercross breeding of diabetes-prone DP with DR BB rats. Iddm 1 in the BioBreeding (BB) rat designates the genomic region on rat Chromosome (Chr) 4 that harbors the gene causing peripheral T cell lymphopenia (Lyp) and diabetes. The average age of onset of diabetes was 85 +/- 53 days of age after the first and 67 +/- 10 days of age after the 9th cycle.
Last Known Status: Unknown





References


Region

Strain QTL Data
Symbol Name Trait
Cia13 Collagen induced arthritis QTL 13 joint integrity trait   (VT:0010548)    
Cia15 Collagen induced arthritis QTL 15 joint integrity trait   (VT:0010548)    
Cia16 Collagen induced arthritis QTL 16 joint integrity trait   (VT:0010548)    
Cia17 Collagen induced arthritis QTL 17 joint integrity trait   (VT:0010548)    
Cia18 Collagen induced arthritis QTL 18 joint integrity trait   (VT:0010548)    
Cia19 Collagen induced arthritis QTL 19 joint integrity trait   (VT:0010548)    
Cia6 Collagen induced arthritis QTL 6 joint integrity trait   (VT:0010548)    
Cia7 Collagen induced arthritis QTL 7 joint integrity trait   (VT:0010548)    
Ciaa4 CIA Autoantibody QTL 4 blood autoantibody amount   (VT:0003725)    
Ciaa5 CIA Autoantibody QTL 5 blood autoantibody amount   (VT:0003725)    
Iddm2 Insulin dependent diabetes mellitus QTL 2 blood glucose amount   (VT:0000188)    
Iddm3 Insulin dependent diabetes mellitus QTL 3 blood glucose amount   (VT:0000188)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics This strain is Diabetic Resistant. 61032
strain_reproduction Average litter size at weaning 7.2 pups for the diabetic-resistant colonies. 61032

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-04-06 BBDR/Rhw    BBDR/Rhw    Name updated 68913 APPROVED
2010-09-20 BBDR/Rhw    BBDR/Rhw    Name updated 68913 APPROVED
2010-09-20 BBDR/Rhw    BBDR/Rhw    Name updated 68913 APPROVED