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Strain Registration

Strain: DA.E3-(D20Rat42-D20Rat49)/Rhd

Symbol: DA.E3-(D20Rat42-D20Rat49)/Rhd
Strain: DA.E3-(D20Rat42-D20Rat49)
Substrain: Rhd
RGD ID: 10002743
Citation ID: RRID:RGD_10002743
Ontology ID: RS:0003878
Previously known as: DA.E3-(D20Rat42-D20Rat49)/Rhd; DA.1I
Type: congenic
Source: Section for Medical Inflammation Research, Lund University, Lund, Sweden.
Origin: A fragment containing MHC region from E3/ZtmRhd was introduced in DA/ZtmRhd by marker-assisted breeding and verified as pure congenic line after six generations of backcross to DA/ZtmRhd.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,459,698 - 8,042,534RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0204,186,104 - 8,654,464RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0206,265,460 - 10,844,146RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4204,582,054 - 8,286,657RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
joint swelling  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. The major histocompatibility complex genes are associated with basal pain sensitivity differences between Dark-Agouti and novel congenic DA.1U rats. Guo Y, etal., Life Sci. 2010 Jun 19;86(25-26):972-8. doi: 10.1016/j.lfs.2010.05.006. Epub 2010 May 13.
2. Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat. Holmberg J, etal., J Immunol. 2006 Jan 15;176(2):1172-9.
3. Susceptibility of DA rats to arthritis induced with adjuvant oil or rat collagen is determined by genes both within and outside the major histocompatibility complex. Lorentzen JC and Klareskog L, Scand J Immunol 1996 Dec;44(6):592-8.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D20Rat42)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2204,459,698 - 4,459,841 (-)MAPPER
Rnor_6.0204,186,104 - 4,186,246NCBI
Rnor_5.0206,265,460 - 6,265,602UniSTS
RGSC_v3.4204,582,055 - 4,582,197UniSTS
RGSC_v3.4204,582,054 - 4,582,198RGD
RGSC_v3.1204,582,281 - 4,582,425RGD
SHRSP x BN Map200.0UniSTS
SHRSP x BN Map200.0RGD
Cytogenetic Map20p12UniSTS

Flank 2 / 1 (D20Rat49)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2208,042,410 - 8,042,534 (+)MAPPER
Rnor_6.0208,654,341 - 8,654,464NCBI
Rnor_5.02010,844,023 - 10,844,146UniSTS
RGSC_v3.4208,286,534 - 8,286,657UniSTS
RGSC_v3.4208,286,533 - 8,286,657RGD
RGSC_v3.1208,286,761 - 8,286,884RGD
Celera209,573,432 - 9,573,555UniSTS
RH 3.4 Map20105.9RGD
RH 3.4 Map20105.9UniSTS
RH 2.0 Map20112.8RGD
SHRSP x BN Map206.84RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics These have the i allele from the MHC class I (RT1-A) 10002742

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-23 DA.E3-(D20Rat42-D20Rat49)/Rhd    E3.DA-(D20Rat42-D20Rat49)/Rhd    Symbol updated 68687 APPROVED
2015-04-23 DA.E3-(D20Rat42-D20Rat49)/Rhd    E3.DA-(D20Rat42-D20Rat49)/Rhd    Name updated 68913 APPROVED
2015-04-23 DA.E3-(D20Rat42-D20Rat49)/Rhd    E3.DA-(D20Rat42-D20Rat49)/Rhd    Symbol updated 68687 APPROVED
2015-04-23 DA.E3-(D20Rat42-D20Rat49)/Rhd    E3.DA-(D20Rat42-D20Rat49)/Rhd    Name updated 68913 APPROVED