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Strain: BBDP/Rhw

Symbol: BBDP/Rhw
Strain: BBDP
Substrain: Rhw
RGD ID: 10002
Citation ID: RRID:RGD_10002
Ontology ID: RS:0000071
Type: inbred
Source: Not Available
Origin: S. Bieg and coworkers (1998) generated a congenic line in which diabetes and lymphopenia are controlled solely by Iddm 1. This strain was generated by nine cycles of cross-intercross breeding of diabetes-prone DP with DR BB rats. Iddm 1 in the BioBreeding (BB) rat designates the genomic region on rat Chromosome (Chr) 4 that harbors the gene causing peripheral T cell lymphopenia (Lyp) and diabetes. The average age of onset of diabetes was 85 ± 53 days of age after the first and 67 ± 10 days of age after the 9th cycle.
Last Known Status: Unknown

Disease Annotations     Click to see Annotation Detail View



Strain QTL Data
Symbol Name Trait
Iddm1 Insulin dependent diabetes mellitus QTL 1 blood glucose amount   (VT:0000188)    
Iddm2 Insulin dependent diabetes mellitus QTL 2 blood glucose amount   (VT:0000188)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics This strain is Diabetic Prone 61032
strain_infection These are infected by Ljungan virus (LV) which induces glucose intolerance 1601199
strain_reproduction Average litter size at weaning 6.5 pups for diabetic-prone colonies. 61032