Sh2b3em1Mcwi-var1Rat Genome Database

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Variant: Sh2b3em1Mcwi-var1 -  Rattus norvegicus

Name: Sh2b3em1Mcwi-var1
RGD ID: 14349034
Description: Variant associated with allele Sh2b3em1Mcwi; this allele was made by zinc finger nuclease mutagenesis. The resulting mutation is an in-frame 6-bp deletion in exon 2 (del 847-852).
Type: deletion (SO:0000159)
Associated Allele:  Sh2b3em1Mcwi
Reference Nucleotide: CACTTG
Variant Nucleotide:
Position
Rat AssemblyChrPosition (strand)Source
mRatBN7.21234,750,772 - 34,750,777 (+)RGD
Rnor_6.01240,262,913 - 40,262,918 (+)RGD
Aliases: NC_005111.4:g.40262913_40262918del




Related Rat Strains
The following Strains have been annotated to Sh2b3em1Mcwi-var1
SS-Sh2b3em1Mcwi-/+     SS-Sh2b3em1Mcwi-/-     SS-Sh2b3em1Mcwi    


References - curated
# Reference Title Reference Citation
1. Mutation of SH2B3 (LNK), a genome-wide association study candidate for hypertension, attenuates Dahl salt-sensitive hypertension via inflammatory modulation. Rudemiller NP, etal., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16.

Additional Information