RGD Reference Report - Use of simple sequence length polymorphisms for genetic characterization of rat inbred strains. - Rat Genome Database
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Use of simple sequence length polymorphisms for genetic characterization of rat inbred strains.

Authors: Otsen, M  Den Bieman, M  Winer, ES  Jacob, HJ  Szpirer, J  Szpirer, C  Bender, K  Van Zutphjen, LF 
Citation: Otsen M, etal., Mamm Genome 1995 Sep;6(9):595-601.
RGD ID: 737874
Pubmed: (View Article at PubMed) PMID:8535065

Genetic monitoring is an essential component of colony management and for the rat has been accomplished primarily by using immunological and biochemical markers. Here, we report that simple sequence length polymorphisms (SSLPs) are a faster and more economical way of monitoring inbred strains of rats. We characterized 61 inbred strains of rats, using primer pairs for 37 SSLPs. Each of these loci appeared to be highly polymorphic, with the number of alleles per locus ranging between 3 and 14 and, as a result, all the 61 inbred strains tested in this study could be provided with a unique strain profile. These strain profiles are also used for estimating the degree of similarity between strains. This information may provide the rationale in selecting strains for genetic crosses or for other specific purposes.

Annotation

Objects referenced in this article
0 AGUS/OlaHsd null All species
0 AO/OlaHsd null All species
0 AS/Ztm null All species
0 AUG/OlaHsd null All species
0 AVN/Orl null All species
0 BBWB/Mol null All species
0 BDE/Ztm null All species
0 BDII/Ztm null All species
0 BDIV/lfz null All species
0 BDIX/Orl null All species
0 BDVII/Cub null All species
0 BDX/Cub null All species
0 BH/Ztm null All species
0 BN/Maas null All species
0 BP/Cub null All species
0 BS/Ztm null All species
0 BUF/Ztm null All species
0 CAP/Kuv null All species
0 CHOC/Cub null All species
0 COP/OlaHsd null All species
0 DA/Ztm null All species
0 E3/Ztm null All species
0 F344/Ztm null All species
0 GC/Kun null All species
0 LE/Ztm null All species
0 LEP/Cub null All species
0 LEW/Maas null All species
0 LH/Ztu null All species
0 LOU/CHan Louvain All species
0 MHS/Gib Milan Hypertensive Strain All species
0 MNS/Gib Milan Normotensive Strain All species
0 MWF/Hsd Munich Wistar Fromter All species
0 NAR/SaU non-albumin rat All species
0 NEDH/K null All species
0 OKA/Wsl null All species
0 OM/Ztm Osborne-Mendel All species
0 PAR/Wsl null All species
0 PVG/OlaHsd null All species
0 R/A null All species
0 RHA/Kun Roman high avoidance All species
0 SD/Rij null All species
0 SDH/Ztu null All species
0 SDL/Ipcv null All species
0 SHRSP/Rivm null All species
0 SPRD/Ztm null All species
0 SR/JrIpcv null All species
0 SS/JrIpcv null All species
0 U/A null All species
0 WAG/Rij null All species
0 WF/Ztm null All species
0 WIST/Nhg Wistar All species
0 WOKA/K null All species
0 WOKW/K null All species

Additional Information