RGD Reference Report - Use of simple sequence length polymorphisms for genetic characterization of rat inbred strains. - Rat Genome Database

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Use of simple sequence length polymorphisms for genetic characterization of rat inbred strains.

Authors: Otsen, M  Den Bieman, M  Winer, ES  Jacob, HJ  Szpirer, J  Szpirer, C  Bender, K  Van Zutphjen, LF 
Citation: Otsen M, etal., Mamm Genome 1995 Sep;6(9):595-601.
RGD ID: 737874
Pubmed: PMID:8535065   (View Abstract at PubMed)

Genetic monitoring is an essential component of colony management and for the rat has been accomplished primarily by using immunological and biochemical markers. Here, we report that simple sequence length polymorphisms (SSLPs) are a faster and more economical way of monitoring inbred strains of rats. We characterized 61 inbred strains of rats, using primer pairs for 37 SSLPs. Each of these loci appeared to be highly polymorphic, with the number of alleles per locus ranging between 3 and 14 and, as a result, all the 61 inbred strains tested in this study could be provided with a unique strain profile. These strain profiles are also used for estimating the degree of similarity between strains. This information may provide the rationale in selecting strains for genetic crosses or for other specific purposes.



Objects referenced in this article
Strain AGUS/OlaHsd null Rattus norvegicus
Strain AO/OlaHsd null Rattus norvegicus
Strain AS/Ztm null Rattus norvegicus
Strain AUG/OlaHsd null Rattus norvegicus
Strain AVN/Orl null Rattus norvegicus
Strain BBWB/Mol null Rattus norvegicus
Strain BDE/Ztm null Rattus norvegicus
Strain BDII/Ztm null Rattus norvegicus
Strain BDIV/lfz null Rattus norvegicus
Strain BDIX/Orl null Rattus norvegicus
Strain BDVII/Cub null Rattus norvegicus
Strain BDX/Cub null Rattus norvegicus
Strain BH/Ztm null Rattus norvegicus
Strain BN/Maas null Rattus norvegicus
Strain BP/Cub null Rattus norvegicus
Strain BS/Ztm null Rattus norvegicus
Strain BUF/Ztm null Rattus norvegicus
Strain CAP/Kuv null Rattus norvegicus
Strain CHOC/Cub null Rattus norvegicus
Strain COP/OlaHsd null Rattus norvegicus
Strain DA/Ztm null Rattus norvegicus
Strain E3/Ztm null Rattus norvegicus
Strain F344/Ztm null Rattus norvegicus
Strain GC/Kun null Rattus norvegicus
Strain LE/Ztm null Rattus norvegicus
Strain LEP/Cub null Rattus norvegicus
Strain LEW/Maas null Rattus norvegicus
Strain LH/Ztu null Rattus norvegicus
Strain LOU/CHan Louvain Rattus norvegicus
Strain MHS/Gib Milan Hypertensive Strain Rattus norvegicus
Strain MNS/Gib Milan Normotensive Strain Rattus norvegicus
Strain MWF/Hsd Munich Wistar Fromter Rattus norvegicus
Strain NAR/SaU non-albumin rat Rattus norvegicus
Strain NEDH/K null Rattus norvegicus
Strain OKA/Wsl null Rattus norvegicus
Strain OM/Ztm Osborne-Mendel Rattus norvegicus
Strain PAR/Wsl null Rattus norvegicus
Strain PVG/OlaHsd null Rattus norvegicus
Strain R/A null Rattus norvegicus
Strain RHA/Kun Roman high avoidance Rattus norvegicus
Strain SD/Rij null Rattus norvegicus
Strain SDH/Ztu null Rattus norvegicus
Strain SDL/Ipcv null Rattus norvegicus
Strain SHRSP/Rivm null Rattus norvegicus
Strain SPRD/Ztm null Rattus norvegicus
Strain SR/JrIpcv null Rattus norvegicus
Strain SS/JrIpcv null Rattus norvegicus
Strain U/A null Rattus norvegicus
Strain WAG/Rij null Rattus norvegicus
Strain WF/Ztm null Rattus norvegicus
Strain WIST/Nhg Wistar Rattus norvegicus
Strain WOKA/K null Rattus norvegicus
Strain WOKW/K null Rattus norvegicus

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