RGD Reference Report - Significant elevation of urinary trypsin inhibitor in patients with brain contusion--a preliminary report. - Rat Genome Database

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Significant elevation of urinary trypsin inhibitor in patients with brain contusion--a preliminary report.

Authors: Sakai, K  Okudera, H  Hongo, K 
Citation: Sakai K, etal., J Clin Neurosci. 2003 Nov;10(6):677-9.
RGD ID: 6904155
Pubmed: PMID:14592616   (View Abstract at PubMed)

Urinary trypsin inhibitor (UTI) is a protease inhibitor, which is produced in the liver. The correlation between UTI level and head injury has not been evaluated. This study was designed to investigate UTI levels in patients with severe head injury. We measured UTI in the urine of patients with brain contusion. UTI was significantly higher in those patients compared to the control group. The results suggest that UTI may be useful for assessing the severity of head injury and also as a treatment marker in patients with brain contusion.



RGD Manual Disease Annotations    Click to see Annotation Detail View

  
Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
AMBPHumanBrain Injuries  IEP protein:increased expression:urineRGD 
AmbpRatBrain Injuries  ISOAMBP (Homo sapiens)protein:increased expression:urineRGD 
AmbpMouseBrain Injuries  ISOAMBP (Homo sapiens)protein:increased expression:urineRGD 

Objects Annotated

Genes (Rattus norvegicus)
Ambp  (alpha-1-microglobulin/bikunin precursor)

Genes (Mus musculus)
Ambp  (alpha 1 microglobulin/bikunin precursor)

Genes (Homo sapiens)
AMBP  (alpha-1-microglobulin/bikunin precursor)


Additional Information