RGD Reference Report - Mapping of rat chromosome 2 markers generated from chromosome-sorted DNA. - Rat Genome Database

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Mapping of rat chromosome 2 markers generated from chromosome-sorted DNA.

Authors: Deng, AY  Jackson, CM  Hoebee, B  Rapp, JP 
Citation: Deng AY, etal., Mamm Genome 1997 Oct;8(10):731-5.
RGD ID: 68909
Pubmed: PMID:9321465   (View Abstract at PubMed)

A quantitative trait locus (QTL) for blood pressure has recently been mapped to a region of roughly 30 cM on rat Chromosome (Chr) 2 by linkage and by the use of congenic strains. For further fine mapping of the QTL, however, closely linked chromosome markers residing in this 30-cM region are required. In the current work, 36 new markers were generated by screening rat Chr 2-sorted DNA libraries and subsequently mapped using five F2 populations. Combining new and existing markers, the marker density for the 30-cM region approaches, on average, one marker per 1.1 cM.

Objects referenced in this article
Marker D2Arb20 D2Arb20 Rattus norvegicus
Marker D5Mgh7 D5Mgh7 Rattus norvegicus
Marker D2Wox8 D2Wox8 Rattus norvegicus
Marker D2Wox7 D2Wox7 Rattus norvegicus
Marker D2Arb9 D2Arb9 Rattus norvegicus
Marker D2Arb24 D2Arb24 Rattus norvegicus
Gene Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 Rattus norvegicus
Gene Camk2d calcium/calmodulin-dependent protein kinase II delta Rattus norvegicus
Gene Fgg fibrinogen gamma chain Rattus norvegicus
Gene Fst follistatin Rattus norvegicus
Gene Htr1a 5-hydroxytryptamine receptor 1A Rattus norvegicus
Gene Npr1 natriuretic peptide receptor 1 Rattus norvegicus
Gene Prlr prolactin receptor Rattus norvegicus

Additional Information