RGD Reference Report - Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat. - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat.

Authors: Szpirer, C  Van Vooren, P  Riviere, M  Cohy S, S  Collau, G  Szpirer, J 
Citation: Szpirer C, etal., Mamm Genome 2000 Sep;11(9):729-35
RGD ID: 61490
Web Url: http://link.springer.de/link/service/journals/00335/bibs/0011009/00110729. htm
Pubmed: PMID:10967130   (View Abstract at PubMed)

In order to improve the rat gene map and comparative mapping with the human and the mouse, we determined the chromosome localization of 54 rat genes. Most genes encode transcription factors or other regulatory proteins of cancer relevance. The human homologs of four genes were also assigned to their respective chromosome. These data generated anchor points between the recently established radiation hybrid maps and the genetic and cytogenetic maps. They improve comparative mapping between the rat, the mouse, and the human gene maps, and in particular they disclose four new synteny groups conserved in the rat and the human. These new localizations should also be useful for the identification of genes involved in the control of quantitative traits such as cancer susceptibility or diabetes.



Gene Ontology Annotations    Click to see Annotation Detail View

Molecular Function

  
Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
Nr1i2Ratnuclear receptor activity  IDA  RGD 

Objects Annotated

Genes (Rattus norvegicus)
Nr1i2  (nuclear receptor subfamily 1, group I, member 2)

Objects referenced in this article
Gene Klf3 Kruppel-like transcription factor 3 (basic) Mus musculus
Gene Timp4 tissue inhibitor of metalloproteinase 4 Mus musculus
Gene Adam2 ADAM metallopeptidase domain 2 Rattus norvegicus
Gene Aldoc aldolase, fructose-bisphosphate C Rattus norvegicus
Gene Btg2 BTG anti-proliferation factor 2 Rattus norvegicus
Gene Camk2a calcium/calmodulin-dependent protein kinase II alpha Rattus norvegicus
Gene Cd82 Cd82 molecule Rattus norvegicus
Gene Cdkn1b cyclin-dependent kinase inhibitor 1B Rattus norvegicus
Gene Ceacam1 CEA cell adhesion molecule 1 Rattus norvegicus
Gene Cebpa CCAAT/enhancer binding protein alpha Rattus norvegicus
Gene Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus
Gene Dbp D-box binding PAR bZIP transcription factor Rattus norvegicus
Gene Ddit3 DNA-damage inducible transcript 3 Rattus norvegicus
Gene Fabp3 fatty acid binding protein 3 Rattus norvegicus
Gene Gata2 GATA binding protein 2 Rattus norvegicus
Gene Gckr glucokinase regulator Rattus norvegicus
Gene Hnf1b HNF1 homeobox B Rattus norvegicus
Gene Hnf4a hepatocyte nuclear factor 4, alpha Rattus norvegicus
Gene Htr5b 5-hydroxytryptamine (serotonin) receptor 5B Rattus norvegicus
Gene Ifrd1 interferon-related developmental regulator 1 Rattus norvegicus
Gene Jak1 Janus kinase 1 Rattus norvegicus
Gene Khk ketohexokinase Rattus norvegicus
Gene Klf3 KLF transcription factor 3 Rattus norvegicus
Gene Klf6 KLF transcription factor 6 Rattus norvegicus
Gene Matk megakaryocyte-associated tyrosine kinase Rattus norvegicus
Gene Mybbp1a MYB binding protein 1a Rattus norvegicus
Gene Nfia nuclear factor I/A Rattus norvegicus
Gene Nfic nuclear factor I/C Rattus norvegicus
Gene Nfix nuclear factor I X Rattus norvegicus
Gene Nppb natriuretic peptide B Rattus norvegicus
Gene Osm oncostatin M Rattus norvegicus
Gene Pawr pro-apoptotic WT1 regulator Rattus norvegicus
Gene Pten phosphatase and tensin homolog Rattus norvegicus
Gene Rasgrp1 RAS guanyl releasing protein 1 Rattus norvegicus
Gene Rem2 RRAD and GEM like GTPase 2 Rattus norvegicus
Gene Serpinb5 serpin family B member 5 Rattus norvegicus
Gene Smad4 SMAD family member 4 Rattus norvegicus
Gene Tcf20 transcription factor 20 Rattus norvegicus
Gene Tgfb1 transforming growth factor, beta 1 Rattus norvegicus
Gene Timp4 TIMP metallopeptidase inhibitor 4 Rattus norvegicus
Gene Trh thyrotropin releasing hormone Rattus norvegicus
Gene Ucp2 uncoupling protein 2 Rattus norvegicus
Gene Wnt7a Wnt family member 7A Rattus norvegicus

Additional Information