RGD Reference Report - KL-6 as a serologic indicator of Pneumocystis carinii pneumonia in immunocompromised hosts. - Rat Genome Database

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KL-6 as a serologic indicator of Pneumocystis carinii pneumonia in immunocompromised hosts.

Authors: Hamada, H  Kohno, N  Yokoyama, A  Hirasawa, Y  Hiwada, K  Sakatani, M  Ueda, E 
Citation: Hamada H, etal., Intern Med. 1998 Mar;37(3):307-10.
RGD ID: 5131424
Pubmed: PMID:9617869   (View Abstract at PubMed)

KL-6, a serum marker for interstitial pneumonitis, was evaluated in patients with Pneumocystis carinii pneumonia (PCP). Patient 1 was a 56-year-old woman with rheumatoid arthritis treated with immunosuppressive drugs and corticosteroids. Patient 2 was a 59-year-old man with a glioblastoma who received anti-cancer drugs and corticosteroids. In both patients, serum KL-6 showed an abnormally high level due to the complication of PCP, and it decreased following successful treatment. These results indicate that PCP is one of the diseases in which serum KL-6 increases.



RGD Manual Disease Annotations    Click to see Annotation Detail View

  
Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
MUC1Humanpneumocystosis  IEP protein:increased expression:serumRGD 
Muc1Ratpneumocystosis  ISOMUC1 (Homo sapiens)protein:increased expression:serumRGD 
Muc1Mousepneumocystosis  ISOMUC1 (Homo sapiens)protein:increased expression:serumRGD 

Objects Annotated

Genes (Rattus norvegicus)
Muc1  (mucin 1, cell surface associated)

Genes (Mus musculus)
Muc1  (mucin 1, transmembrane)

Genes (Homo sapiens)
MUC1  (mucin 1, cell surface associated)


Additional Information