RGD Reference Report - Isolation of a factor that protects against lead inhibition of hepatic and erythrocytic uroporphyrinogen I synthetase activity. - Rat Genome Database

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Isolation of a factor that protects against lead inhibition of hepatic and erythrocytic uroporphyrinogen I synthetase activity.

Authors: Piper, W N  Van Lier, R B 
Citation: Piper WN and Van Lier RB, Life Sci. 1976 Oct 15;19(8):1225-34. doi: 10.1016/0024-3205(76)90258-7.
RGD ID: 25440497
Pubmed: PMID:994723   (View Abstract at PubMed)
DOI: DOI:10.1016/0024-3205(76)90258-7   (Journal Full-text)

Abstract for this paper unavailable



Gene-Chemical Interaction Annotations    Click to see Annotation Detail View

  
Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
HMBSHumanlead(II) chloride decreases activityISORGD:2801Lead Chloride decreases activity of purified Hmbs proteinRGD 
HmbsRatlead(II) chloride decreases activityEXP Lead Chloride decreases activity of purified Hmbs proteinRGD 
HmbsMouselead(II) chloride decreases activityISORGD:2801Lead Chloride decreases activity of purified Hmbs proteinRGD 

Gene Ontology Annotations    Click to see Annotation Detail View

Biological Process

  
Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
HmbsRatporphyrin-containing compound biosynthetic process  IDA Urophorphyrin IRGD 
HmbsRatporphyrin-containing compound metabolic process  IDA PorphobilinogenRGD 

Molecular Function

  
Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
HmbsRathydroxymethylbilane synthase activity  IDA  RGD 

Objects Annotated

Genes (Rattus norvegicus)
Hmbs  (hydroxymethylbilane synthase)

Genes (Mus musculus)
Hmbs  (hydroxymethylbilane synthase)

Genes (Homo sapiens)
HMBS  (hydroxymethylbilane synthase)


Additional Information